The chemical class denominated as PRAMEF13 Inhibitors is specifically designed to modulate the activity of the PRAMEF13 protein. Within the larger context of the PRAME (preferentially expressed antigen in melanoma) family, PRAMEF13 is believed to contribute to various cellular functions, including gene regulation and immune responses. Inhibitors targeting PRAMEF13 are developed to interfere with its normal functions, potentially disrupting the molecular interactions and signaling pathways in which PRAMEF13 engages. This interference may lead to alterations in gene expression patterns and could impact immune-related processes governed by PRAMEF13.
The presumed mechanism of action for PRAMEF13 inhibitors involves their selective binding to the PRAMEF13 protein, thereby modulating its activity and potentially influencing downstream cellular pathways. These inhibitors serve as valuable tools for researchers aiming to unravel the specific functions of PRAMEF13 within the intricate landscape of cellular biology. In this theoretical scenario, the study of PRAMEF13 inhibitors contributes to our understanding of the regulatory mechanisms that govern gene expression and immune responses, providing insights into the complex molecular processes orchestrated by PRAMEF13. By elucidating the role of PRAMEF13 and exploring the consequences of its inhibition, researchers contribute to foundational knowledge in cellular processes and molecular networks, fostering a basis for further investigations in basic scientific research.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $206.00 $299.00 $485.00 | 10 | |
As a PARP inhibitor, olaparib may influence DNA repair mechanisms and chromatin structure, potentially affecting gene expression. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
This compound is a nucleotide analog that can be incorporated into RNA and DNA, potentially disrupting normal gene expression. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
An inhibitor of the Hedgehog signaling pathway, cyclopamine might impact the transcription of various target genes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, LY294002, could alter multiple signaling pathways and potentially affect the expression of genes like PRAMEF13. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
By inhibiting dihydrofolate reductase, methotrexate can lead to a reduction in nucleotide synthesis and potentially affect gene expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
ATRA can regulate gene expression by activating retinoic acid receptors, possibly affecting the expression of PRAMEF13. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $150.00 $920.00 | 5 | |
This tyrosine kinase inhibitor might modulate various pathways involved in cell growth and differentiation, influencing gene expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that might broadly affect protein synthesis and gene expression patterns, including those of PRAMEF13. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $126.00 $278.00 $984.00 | 3 | |
A DNA methyltransferase inhibitor that can lead to demethylation of gene promoters, potentially affecting their expression. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
As a BCR-ABL tyrosine kinase inhibitor, imatinib might influence downstream signaling pathways and gene expression. | ||||||