PPIAL4B Activators constitute a specialized category of chemical compounds or molecules designed or discovered with the specific aim of modulating the activity of the PPIAL4B gene. PPIAL4B, or Peptidylprolyl Isomerase A-Like 4B, is a protein-coding gene found in humans and other organisms. It belongs to the peptidyl-prolyl cis-trans isomerase (PPIase) family, which includes enzymes that catalyze the isomerization of peptide bonds between cis and trans conformations, a critical process in protein folding and conformational changes.
The study of PPIAL4B activators is intriguing because it offers researchers a means to explore the precise role of the PPIAL4B gene in cellular physiology and molecular mechanisms related to protein folding and conformational dynamics. Activation of PPIAL4B can provide valuable insights into its potential involvement in facilitating the proper folding of proteins, thereby influencing their stability and functionality. By manipulating the activity of PPIAL4B through these activators, scientists aim to gain a deeper understanding of the intricate molecular pathways and cellular functions that rely on the gene product, contributing to the broader knowledge of protein folding, conformational changes, and cellular behavior. Consequently, PPIAL4B activators serve as essential tools for researchers dedicated to unraveling the complex molecular mechanisms that govern cellular biology, particularly within the context of protein structure and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG modulates various signaling pathways and could hypothetically upregulate genes by affecting transcription factor activity. | ||||||
Sodium Salicylate | 54-21-7 | sc-3520 sc-3520A sc-3520B sc-3520C | 1 g 25 g 500 g 1 kg | $10.00 $25.00 $80.00 $136.00 | 8 | |
Sodium salicylate may influence nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling, potentially altering gene expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK), which might lead to changes in transcription factor activity and gene expression. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor that could modify the activity of transcription factors regulated by this kinase, thereby influencing gene expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor which might lead to altered transcriptional regulation through the AKT signaling pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an inhibitor of MEK, which could affect downstream ERK signaling and potentially modify gene expression profiles. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR signaling, which can lead to altered transcriptional programs in response to cellular growth signals. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor that could affect AKT signaling and thereby potentially modulate gene transcription. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a MEK inhibitor that might alter ERK pathway signaling, potentially affecting gene expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 inhibits the proteasome, leading to increased levels of proteins including transcription factors, which could influence gene expression. | ||||||