Date published: 2026-1-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

POU6F2 Inhibitors

POU6F2 inhibitors belong to a specific chemical class characterized by their ability to selectively modulate the activity of the POU6F2 protein. POU6F2, or POU class 6 homeobox 2, is a transcription factor that plays a crucial role in the regulation of gene expression. Transcription factors are proteins that bind to DNA and influence the transcription of genetic information into RNA, thereby controlling the synthesis of proteins within a cell. POU6F2, in particular, is known to be involved in the developmental processes of various tissues and organs, making it an attractive target for pharmacological intervention.

The inhibitors designed to interact with POU6F2 are carefully crafted molecules that possess the ability to disrupt the normal functioning of this transcription factor. These compounds typically exhibit high specificity for POU6F2, selectively binding to its active site or regulatory regions, and thereby modulating its transcriptional activity. The intricate molecular interactions between POU6F2 inhibitors and the target protein may involve hydrogen bonding, hydrophobic interactions, or other specific binding motifs. By altering the function of POU6F2, these inhibitors influence downstream gene expression patterns, opening avenues for research into the fundamental biological processes governed by POU6F2. The development and study of POU6F2 inhibitors contribute to our understanding of gene regulation mechanisms, paving the way for advancements in basic biological research and providing valuable insights into the intricacies of cellular development and differentiation.

SEE ALSO...

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$231.00
$863.00
1
(0)

Binds to BET bromodomains, potentially disrupting protein-protein interactions involving POU6F2.

I-BET 151 Hydrochloride

1300031-49-5 (non HCl Salt)sc-391115
10 mg
$450.00
2
(0)

Targets BET bromodomains, possibly altering chromatin state and transcription factor activity.

4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide

1395084-25-9sc-480120
5 mg
$300.00
(0)

Inhibits BRD4, a BET family member, which may affect transcription factors like POU6F2.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$90.00
$212.00
24
(2)

HDAC inhibitor, can change chromatin structure potentially affecting POU6F2-mediated transcription.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

HDAC inhibitor, alters histone acetylation, possibly influencing POU6F2 activity.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$131.00
$515.00
2
(1)

DNA methyltransferase inhibitor, could alter gene expression profiles relevant to POU6F2.

SGC-CBP30

1613695-14-9sc-473871
sc-473871A
5 mg
10 mg
$178.00
$338.00
(0)

CBP/p300 inhibitor, may disrupt transcription factor complexes involving POU6F2.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Inhibits multiple transcription factors, could affect POU6F2 by altering transcriptional networks.

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$53.00
$89.00
7
(1)

Aldehyde dehydrogenase inhibitor, indirectly may affect transcription factor function.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Inhibits various transcription factors, could disrupt POU6F2 pathways.