PLA2 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Melittin | 37231-28-0 | sc-200868 sc-200868A sc-200868B | 500 µg 1 mg 10 mg | $192.00 $332.00 $772.00 | 2 | |
Melittin, a peptide derived from bee venom, exhibits potent phospholipase A2 (PLA2) activity, characterized by its ability to interact with phospholipid bilayers. It disrupts membrane integrity, facilitating the hydrolysis of phospholipids into free fatty acids and lysolipids. The amphipathic nature of melittin enhances its binding affinity to membranes, promoting rapid reaction kinetics. This unique interaction alters membrane fluidity and influences cellular processes, highlighting its role in lipid remodeling. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $68.00 $210.00 $780.00 $1880.00 | 19 | |
N-Ethylmaleimide is a reactive compound that selectively modifies thiol groups in proteins, impacting their function. As a phospholipase A2 (PLA2) inhibitor, it engages in specific covalent interactions with cysteine residues, altering enzyme activity and stability. This modification can lead to changes in lipid metabolism pathways, influencing cellular signaling and membrane dynamics. Its unique reactivity and specificity make it a valuable tool for studying enzyme mechanisms and lipid interactions. | ||||||
Mastoparan | 72093-21-1 | sc-200831 | 1 mg | $97.00 | ||
Mastoparan is a potent peptide that acts as a phospholipase A2 (PLA2) activator, facilitating the hydrolysis of phospholipids. It interacts with membrane bilayers, inducing structural changes that enhance enzyme accessibility. This interaction promotes rapid lipid turnover and influences cellular signaling cascades. Mastoparan's unique ability to modulate membrane dynamics and its role in activating PLA2 highlight its significance in understanding lipid-mediated processes and cellular responses. | ||||||
PLA2 activator | sc-3034 | 0.5 mg | $95.00 | 3 | ||
PLA2 activator is a specialized compound that enhances the activity of phospholipase A2 enzymes by stabilizing their active conformation. It engages in specific molecular interactions with lipid membranes, promoting the release of fatty acids and lysolipids. This activation leads to altered membrane fluidity and influences downstream signaling pathways. The kinetic profile of PLA2 activator showcases its rapid engagement with target enzymes, underscoring its role in lipid metabolism and cellular homeostasis. | ||||||