Date published: 2026-1-22

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PKM Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PKM Antibodies for studying pyruvate kinase M (PKM), a key enzyme in the glycolytic pathway. PKM Antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PKM plays a crucial role in cellular metabolism by regulating the conversion of phosphoenolpyruvate to pyruvate, thereby influencing energy production and metabolic flux. PKM activity is essential for maintaining the balance between glycolysis and gluconeogenesis, making it a significant factor in cancer metabolism and other metabolic disorders. Understanding PKM function and regulation opens new possibilities for therapeutic strategies targeting metabolic pathways. Researchers worldwide rely on PKM monoclonal antibodies to advance their metabolic research projects. PKM investigation continues to reveal new insights into cellular energy mechanisms and disease pathways. Santa Cruz Biotechnology monoclonal antibodies for PKM support researchers in their quest to unlock new therapeutic approaches for metabolic disorders and cancer treatment.

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PKM Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PKM Antibody (C-11)

sc-365684mouse IgG2a κ454-513 (h)WB, IP, IF, IHC(P), ELISAm, r, h
46
(33)

PKM Antibody (YY-3)

sc-100538mouse IgM1-532 (h)WB, IP, ELISAm, r, h
2
(3)

PKM CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PKM CRISPR/Cas9 KO Plasmid (h2)

sc-400834-KO-2hGene KnockoutGFP0
(0)

PKM HDR Plasmid (h2)

sc-400834-HDR-2hHomology Directed RepairPuromycin0
(0)

PKM Double Nickase Plasmid (h)

sc-400834-NIChGene KnockoutPuromycin0
(0)

PKM Double Nickase Plasmid (h2)

sc-400834-NIC-2hGene KnockoutPuromycin0
(0)

PKM siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PKM siRNA (h)

sc-62820hGene SilencingN/A
14
(0)

PKM shRNA Plasmid (h)

sc-62820-SHhGene SilencingPuromycin
14
(0)

PKM shRNA (h) Lentiviral Particles

sc-62820-VhGene SilencingPuromycin
14
(0)

PKM siRNA (m)

sc-62821mGene SilencingN/A
1
(0)

PKM shRNA Plasmid (m)

sc-62821-SHmGene SilencingPuromycin
1
(0)

PKM shRNA (m) Lentiviral Particles

sc-62821-VmGene SilencingPuromycin
1
(0)