Date published: 2025-12-17

1-800-457-3801

SCBT Portrait Logo
Seach Input

PKC α Substrates

Santa Cruz Biotechnology now offers a broad range of PKCα Substrates for use in various applications. PKCα Substrates are crucial tools for studying the activity and specificity of protein kinase C alpha (PKCα), an enzyme involved in regulating a multitude of cellular processes, including signal transduction, gene expression, cell proliferation, and differentiation. By providing specific substrates for PKCα, researchers can accurately measure its kinase activity and investigate the phosphorylation events mediated by this enzyme. These substrates are essential for understanding how PKCα modulates various signaling pathways and cellular functions. In scientific research, PKCα Substrates are used to explore the downstream effects of PKCα activation, such as the regulation of target proteins involved in calcium signaling, membrane dynamics, and cytoskeletal organization. Researchers employ these substrates to study the role of PKCα in different cellular contexts and to study the complex signaling networks it regulates. Additionally, PKCα Substrates are valuable in high-throughput screening assays aimed at identifying potential inhibitors or activators of PKCα, aiding in the discovery of new regulatory mechanisms. The use of PKCα Substrates supports the development of experimental models to dissect the intricate interactions between PKCα and other signaling molecules, enhancing our understanding of cellular regulation and adaptation. By enabling precise measurement and manipulation of PKCα activity, these substrates facilitate detailed studies of PKCα's role in cellular physiology. View detailed information on our available PKCα Substrates by clicking on the product name.

SEE ALSO...

Items 21 to 23 of 23 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

FAK (Ser 722)

sc-24545
0.5 mg/0.1 ml
$95.00
1
(0)

FAK (Ser 722) plays a pivotal role in cellular signaling by modulating focal adhesion dynamics and cytoskeletal organization. Phosphorylation at Ser 722 enhances its interaction with various signaling proteins, facilitating the activation of downstream pathways involved in cell migration and survival. This modification influences the kinetics of protein-protein interactions, promoting a cascade of events that regulate cellular responses to mechanical stress and growth factors, ultimately shaping cellular architecture and function.

Rb (Thr 821/826)

sc-24551
0.5 mg/0.1 ml
$95.00
(0)

Rb (Thr 821/826) is integral to the regulation of cellular processes, particularly in the context of signal transduction. Its phosphorylation at Thr 821/826 enhances binding affinity to specific substrates, influencing the activation of PKC alpha pathways. This modification alters the kinetics of downstream signaling cascades, impacting cellular proliferation and differentiation. The unique interactions fostered by Rb contribute to the fine-tuning of cellular responses to environmental stimuli, underscoring its role in maintaining cellular homeostasis.

IRS-1 (Ser 270)

sc-24558
0.5 mg/0.1 ml
$95.00
(0)

IRS-1 (Ser 270) plays a pivotal role in modulating insulin signaling pathways through its phosphorylation at Ser 270. This modification enhances its interaction with the p85 regulatory subunit of PI3K, facilitating the recruitment of downstream effectors. The resulting signaling cascade influences glucose uptake and metabolism. IRS-1's unique structural conformation allows for specific protein-protein interactions, which are crucial for the amplification of metabolic responses to insulin.