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Items 21 to 23 of 23 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
FAK (Ser 722) | sc-24545 | 0.5 mg/0.1 ml | $95.00 | 1 | ||
FAK (Ser 722) plays a pivotal role in cellular signaling by modulating focal adhesion dynamics and cytoskeletal organization. Phosphorylation at Ser 722 enhances its interaction with various signaling proteins, facilitating the activation of downstream pathways involved in cell migration and survival. This modification influences the kinetics of protein-protein interactions, promoting a cascade of events that regulate cellular responses to mechanical stress and growth factors, ultimately shaping cellular architecture and function. | ||||||
Rb (Thr 821/826) | sc-24551 | 0.5 mg/0.1 ml | $95.00 | |||
Rb (Thr 821/826) is integral to the regulation of cellular processes, particularly in the context of signal transduction. Its phosphorylation at Thr 821/826 enhances binding affinity to specific substrates, influencing the activation of PKC alpha pathways. This modification alters the kinetics of downstream signaling cascades, impacting cellular proliferation and differentiation. The unique interactions fostered by Rb contribute to the fine-tuning of cellular responses to environmental stimuli, underscoring its role in maintaining cellular homeostasis. | ||||||
IRS-1 (Ser 270) | sc-24558 | 0.5 mg/0.1 ml | $95.00 | |||
IRS-1 (Ser 270) plays a pivotal role in modulating insulin signaling pathways through its phosphorylation at Ser 270. This modification enhances its interaction with the p85 regulatory subunit of PI3K, facilitating the recruitment of downstream effectors. The resulting signaling cascade influences glucose uptake and metabolism. IRS-1's unique structural conformation allows for specific protein-protein interactions, which are crucial for the amplification of metabolic responses to insulin. | ||||||