PIK3IP1 Inhibitors
Chemicals that can inhibit PIK3IP1 signaling by activating the PI3K/AKT pathway are diverse in their function and targets. These include various growth factors such as IGF-1, EGF, PDGF, VEGF, FGF-2, NGF, and BDNF, which are known activators of the PI3K/AKT pathway. Activation of the pathway by these factors could lead to a compensatory downregulation or inhibition of PIK3IP1 as a means to maintain cellular homeostasis.
Other chemicals listed here, such as insulin and heregulin, also activate the PI3K/AKT pathway, and could inhibit PIK3IP1 in a similar manner. Further, SC79 and 740 Y-P are direct activators of Akt and PI3K, respectively, and their activation of the pathway could also lead to a compensatory downregulation or inhibition of PIK3IP1.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin is another activator of the PI3K/Akt pathway. Its activation of the pathway could theoretically lead to a compensatory inhibition of PIK3IP1. | ||||||
2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester | 305834-79-1 | sc-479756 | 25 mg | $380.00 | ||
A specific Akt activator that could theoretically downregulate or inhibit PIK3IP1 by activating the PI3K/Akt pathway. | ||||||