Date published: 2025-11-22

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PI 3-kinase C2β Inhibitors

PI3-kinase C2β inhibitors belong to a class of chemical compounds specifically designed to target and inhibit the activity of PI3-kinase C2β (Phosphoinositide 3-kinase C2β). PI3-kinase C2β is an enzyme that plays a significant role in intracellular signaling pathways, regulating various cellular processes such as cell growth, survival, and migration. The inhibitors are carefully designed to interact with the active site or specific binding sites of PI3-kinase C2β, preventing its normal function and activity. The primary focus of these inhibitors is to interfere with the enzymatic activity of PI3-kinase C2β, which catalyzes the conversion of phosphatidylinositol 4-phosphate (PI4P) to phosphatidylinositol 3-phosphate (PI3P). By inhibiting this conversion, these compounds modulate downstream signaling cascades, affecting cellular responses involved in growth, proliferation, and other physiological processes.

PI3-kinase C2β inhibitors are of great interest in scientific research as they offer valuable insights into the regulatory mechanisms of PI3-kinase C2β and its role in intracellular communication. By selectively blocking the enzyme's function, researchers can better understand the specific contributions of PI3-kinase C2β in various cellular contexts and signaling pathways. This class of inhibitors provides a powerful tool to investigate the complex biology of PI3-kinase C2β and its implications in normal cellular physiology. In laboratory settings, PI3-kinase C2β inhibitors are commonly utilized to investigate cellular signaling pathways and unravel the roles of PI3-kinase C2β in various cellular processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Compound 15e

371943-05-4sc-202551
sc-202551A
1 mg
5 mg
$51.00
$206.00
(0)

A specific PI3-kinase C2β inhibitor that has been used in research studies to explore its effects on cellular signaling and functions.

PI-103

371935-74-9sc-203193
sc-203193A
1 mg
5 mg
$32.00
$128.00
3
(1)

This is a dual inhibitor of both PI3-kinase C2β and mTOR (mammalian target of rapamycin), providing a potential synergistic effect on blocking signaling pathways.

AS-252424

900515-16-4sc-202961
sc-202961A
1 mg
5 mg
$41.00
$155.00
(1)

A selective PI3-kinase C2β inhibitor.

CAL-101

870281-82-6sc-364453
10 mg
$189.00
4
(1)

Originally developed as a PI3-kinase delta (δ) inhibitor, CAL-101 also has inhibitory activity against PI3-kinase C2β.

YM201636

371942-69-7sc-204193
5 mg
$213.00
6
(1)

A dual inhibitor of PI3-kinase C2β and Polo-like kinase 1 (PLK1), which are both involved in cell cycle regulation.

PI 3-Kβ Inhibitor VI, TGX-221

663619-89-4sc-203190
1 mg
$437.00
(0)

Although mainly known as a PI3-kinase beta (β) inhibitor, TGX-221 has some inhibitory effects on PI3-kinase C2β as well.