Date published: 2025-10-20

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Phosphoramidites

Santa Cruz Biotechnology now offers a broad range of phosphoramidites for use in various applications. Phosphoramidites are essential reagents in the synthesis of oligonucleotides, which are short sequences of nucleotides crucial for DNA and RNA research. These compounds are widely used in the field of molecular biology, particularly in the process of automated DNA synthesis. Phosphoramidites are valuable in the study of genetic sequences, enabling researchers to create precise and custom sequences of nucleotides for experiments involving gene expression, regulation, and modification. Their role extends to the synthesis of probes and primers, which are integral in polymerase chain reactions (PCR), sequencing technologies, and genetic engineering. In addition to their application in basic research, phosphoramidites are instrumental in the development of diagnostic tools, such as biosensors and assays, which detect specific nucleic acid sequences. This chemical category has revolutionized the way scientists manipulate genetic material, offering high efficiency and accuracy in the creation of synthetic nucleic acids. View detailed information on our available phosphoramidites by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

CruzFluor sm™ 2 phosphoramidite

sc-362582
50 µmol
$186.00
(1)

CruzFluor sm™ 2 phosphoramidite is a specialized phosphoramidite that exhibits exceptional reactivity in oligonucleotide synthesis. Its unique structure facilitates rapid coupling reactions, enhancing the efficiency of nucleotide incorporation. The compound's ability to form stable intermediates allows for precise control over reaction kinetics, while its distinctive electronic properties contribute to improved yield and purity of synthesized products. Additionally, it demonstrates favorable solubility in various solvents, promoting versatile applications in nucleic acid chemistry.

CruzQuench™ 2 phosphoramidite

sc-362637
100 µmol
$244.00
(0)

CruzQuench™ 2 phosphoramidite is a highly reactive phosphoramidite designed for efficient oligonucleotide synthesis. Its unique molecular architecture enables rapid activation and coupling, optimizing reaction pathways. The compound's distinctive steric and electronic characteristics enhance selectivity, minimizing side reactions. Furthermore, it exhibits excellent solubility in a range of organic solvents, facilitating streamlined workflows in nucleic acid research and development.

CruzQuench™ 1 phosphoramidite

sc-362630
100 µmol
$195.00
(0)

CruzQuench™ 1 phosphoramidite is an innovative phosphoramidite that showcases exceptional reactivity and stability in nucleic acid synthesis. Its unique structural features promote efficient phosphitylation, allowing for precise control over reaction kinetics. The compound's tailored sterics and electronics enhance its compatibility with various coupling agents, reducing byproduct formation. Additionally, it demonstrates remarkable solubility in diverse solvents, ensuring optimal performance in complex synthetic environments.

CruzQuench™ 3 phosphoramidite

sc-362646
100 µmol
$195.00
(0)

CruzQuench™ 3 phosphoramidite stands out for its unique ability to facilitate rapid and selective phosphorylation reactions. Its distinctive electronic properties enable enhanced nucleophilicity, promoting efficient coupling with nucleobases. The compound's sterically hindered design minimizes steric clashes, leading to improved reaction yields. Furthermore, its exceptional solubility profile allows for seamless integration into various reaction media, optimizing performance in diverse synthetic applications.

CruzQuench™ 7 phosphoramidite

sc-362681
50 µmol
$295.00
(0)

CruzQuench™ 7 phosphoramidite is characterized by its remarkable stability under ambient conditions, which enhances its usability in synthetic pathways. Its unique steric configuration allows for precise control over reaction kinetics, facilitating selective coupling with oligonucleotides. The compound exhibits strong hydrogen bonding capabilities, promoting effective interactions with target substrates. Additionally, its high solubility in polar solvents ensures compatibility across a range of synthetic environments, streamlining the reaction process.

6-FAM phosphoramidite

sc-363596
100 µmol
$132.00
1
(0)

6-FAM phosphoramidite is distinguished by its ability to form robust covalent bonds during oligonucleotide synthesis, enabling efficient incorporation into nucleic acid sequences. Its unique fluorophore structure enhances fluorescence properties, allowing for sensitive detection in various assays. The compound's reactivity is influenced by its phosphoramidite functional group, which promotes rapid coupling reactions. Furthermore, its solubility in organic solvents aids in achieving high yields in complex synthetic protocols.