CruzFluor™ sm 2 (CFLsm2) family has the spectral properties similar to those of fluoresceins and Alexa Fluor® 488 (Alexa Fluor® is the trademark of Invitrogen). CFLsm2 phosphoramidite enables the oligo labeling with the similar spectral properties and photostability of Alexa Fluor® 488 using the well established phosphoramidite chemistry. Compared to fluoresceins CFLsm2 family has much stronger fluorescence and higher photostability. Additionally their fluorescence is pH-independent from pH 3 to 11. These characteristics make this new dye family a superior alternative to fluoresceins for use in oligo synthesis with an oligo synthesizer.
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