Date published: 2025-9-29

1-800-457-3801

SCBT Portrait Logo
Seach Input

PGI2 Inhibitors

Santa Cruz Biotechnology now offers a broad range of PGI2 Inhibitors for use in various applications. PGI2 Inhibitors are critical tools for studying the functions of prostacyclin (PGI2), a prostaglandin that plays a significant role in vasodilation, inhibition of platelet aggregation, and modulation of inflammation. By inhibiting PGI2, these compounds allow researchers to investigate the pathways and processes regulated by prostacyclin signaling. In scientific research, PGI2 Inhibitors are utilized to explore the mechanisms of PGI2-mediated signal transduction and how blocking these pathways impacts vascular tone, blood flow, and cellular responses. These inhibitors are particularly valuable for studying the role of PGI2 in the cardiovascular system, including its effects on endothelial cell function and smooth muscle relaxation. Researchers also use PGI2 Inhibitors to examine the involvement of prostacyclin in inflammatory processes and its interaction with other signaling molecules and pathways. Additionally, these inhibitors help explain the regulation of platelet function and the prevention of excessive clot formation, providing insights into the complex balance between coagulation and anticoagulation mechanisms. By employing PGI2 Inhibitors, scientists can develop experimental models to study the broader implications of PGI2 signaling in health and disease, advancing our understanding of fundamental biological processes and regulatory networks. View detailed information on our available PGI2 Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

15(S)-HPETE

70981-96-3sc-200966
50 µg
$54.00
(0)

15(S)-HPETE is a key intermediate in the biosynthesis of prostaglandins, exhibiting unique reactivity as a hydroperoxide. Its structure allows for specific interactions with cyclooxygenase enzymes, influencing the conversion to prostaglandin I2. The compound's stability and reactivity are affected by its hydroperoxide group, which can participate in radical reactions, impacting lipid peroxidation pathways. This positions 15(S)-HPETE as a crucial player in cellular signaling and inflammatory responses.

U-51605

64192-56-9sc-205535
sc-205535A
500 µg
1 mg
$309.00
$544.00
(0)

U-51605 is a potent compound that acts as a selective agonist for prostacyclin receptors, facilitating unique molecular interactions that enhance its efficacy. Its structure promotes specific binding affinities, influencing downstream signaling pathways related to vascular homeostasis. The compound's kinetic profile reveals rapid activation and a distinct half-life, allowing for precise modulation of cellular responses. Additionally, its unique stereochemistry contributes to its selective receptor engagement, enhancing its biological impact.