Date published: 2026-4-1

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PEPCK-C Antibodies

Santa Cruz Biotechnology delivers a wide array of PEPCK-C monoclonal antibodies for investigating phosphoenolpyruvate carboxykinase (PEPCK-C) in various metabolic processes. PEPCK-C Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PEPCK-C is a key enzyme in gluconeogenesis and plays a critical role in maintaining glucose homeostasis, particularly during fasting or intense exercise. Its regulation is essential for metabolic flexibility and energy balance, making PEPCK-C an important target for studies related to diabetes, obesity, and metabolic disorders. Understanding the function and regulation of PEPCK-C can provide insights into potential therapeutic strategies for metabolic conditions. Researchers can explore cellular localization, protein interactions, and expression patterns of PEPCK-C using specific detection methods. Advanced research techniques enable detailed analysis of PEPCK-C's role in glucose metabolism and energy homeostasis. Investigating PEPCK-C expression patterns helps reveal its involvement in various physiological and pathological conditions. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of metabolic regulation and developing new therapeutic approaches.

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PEPCK-C Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PEPCK-C/PCK1 Antibody (F-11)

sc-377027mouse IgG2a κ189-221 (h)WB, IP, IF, IHC(P), ELISAm, r, h
9
(4)

PEPCK-C/PCK1 Antibody (A-3)

sc-373972mouse IgG2b κ1-44 (h)WB, IP, IF, ELISAh

new

(3)

PEPCK-C/PCK1 Antibody (G-9)

sc-377136mouse IgG1 κ545-581 (h)WB, IP, IF, ELISAm, r, h
2
(2)

PEPCK-C CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PEPCK-C/PCK1 CRISPR/Cas9 KO Plasmid (h)

sc-401295hGene KnockoutGFP0
(0)

PEPCK-C/PCK1 HDR Plasmid (h)

sc-401295-HDRhHomology Directed RepairPuromycin0
(0)

PEPCK-C CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PEPCK-C/PCK1 CRISPR Activation Plasmid (h)

sc-401295-ACThGene ActivationPuro, Blast, Hygro0
(0)

PEPCK-C/PCK1 CRISPR Activation Plasmid (m)

sc-422131-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PEPCK-C/PCK1 CRISPR Activation Plasmid (m2)

sc-422131-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PEPCK-C siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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PEPCK-C/PCK1 siRNA (h)

sc-76106hGene SilencingN/A
2
(1)

PEPCK-C/PCK1 shRNA Plasmid (h)

sc-76106-SHhGene SilencingPuromycin
2
(1)

PEPCK-C/PCK1 shRNA (h) Lentiviral Particles

sc-76106-VhGene SilencingPuromycin
2
(1)

PEPCK-C/PCK1 siRNA (m)

sc-76107mGene SilencingN/A0
(0)

PEPCK-C/PCK1 shRNA Plasmid (m)

sc-76107-SHmGene SilencingPuromycin0
(0)

PEPCK-C/PCK1 shRNA (m) Lentiviral Particles

sc-76107-VmGene SilencingPuromycin0
(0)

PEPCK-C/PCK1 shRNA Plasmid (r)

sc-270634-SHrGene SilencingPuromycin0
(0)

PEPCK-C/PCK1 shRNA (r) Lentiviral Particles

sc-270634-VrGene SilencingPuromycin0
(0)