Date published: 2025-12-19

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PCDHAC1_Pcdhac1 Inhibitors

The chemical class known as PCDHAC1_Pcdhac1 Inhibitors is designed to selectively modulate the activity of the protocadherin alpha subfamily C member 1 (PCDHAC1 or Pcdhac1) protein. Protocadherins are a family of cell adhesion molecules involved in diverse cellular processes, particularly in neuronal development and synaptic plasticity. PCDHAC1, as a member of this subfamily, likely plays a role in mediating cell-cell interactions, contributing to the formation and maintenance of neuronal circuits. Inhibitors targeting PCDHAC1_Pcdhac1 operate by interfering with the normal functions of this protein, disrupting the intricate molecular interactions and signaling pathways in which PCDHAC1_Pcdhac1 is engaged. This interference may lead to alterations in cell adhesion patterns and could impact cellular communication processes governed by PCDHAC1_Pcdhac1.

The mechanism of action for PCDHAC1_Pcdhac1 inhibitors involves their selective binding to PCDHAC1_Pcdhac1, thereby modulating its activity and potentially influencing downstream cellular processes. These inhibitors could serve as valuable tools for researchers aiming to elucidate the specific functions of protocadherins within the broader context of cellular biology, particularly in the intricate processes of neuronal development and synaptic connectivity. The study of PCDHAC1_Pcdhac1 inhibitors contributes to our understanding of the regulatory mechanisms that govern cell adhesion and communication, providing insights into the complex molecular processes involved in the formation and maintenance of neuronal networks.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cyclopamine

4449-51-8sc-200929
sc-200929A
1 mg
5 mg
$92.00
$204.00
19
(1)

Cyclopamine inhibits the Hedgehog signaling pathway, which could indirectly influence the expression of various genes, including protocadherin family members.

SB-216763

280744-09-4sc-200646
sc-200646A
1 mg
5 mg
$70.00
$198.00
18
(1)

SB216763 is a GSK-3 inhibitor, potentially affecting Wnt signaling and thereby altering the expression of certain genes.

XAV939

284028-89-3sc-296704
sc-296704A
sc-296704B
1 mg
5 mg
50 mg
$35.00
$115.00
$515.00
26
(1)

XAV-939 inhibits Wnt/β-catenin mediated transcription, which could affect gene expression profiles including that of protocadherin genes.

GSK-3 Inhibitor IX

667463-62-9sc-202634
sc-202634A
sc-202634B
1 mg
10 mg
50 mg
$57.00
$184.00
$867.00
10
(1)

BIO is a GSK-3 inhibitor known to activate Wnt signaling, potentially leading to changes in gene expression patterns.

Zebularine

3690-10-6sc-203315
sc-203315A
sc-203315B
10 mg
25 mg
100 mg
$126.00
$278.00
$984.00
3
(1)

Zebularine is a DNA methyltransferase inhibitor that can lead to demethylation of genes and impact their expression.

DAPT

208255-80-5sc-201315
sc-201315A
sc-201315B
sc-201315C
5 mg
25 mg
100 mg
1 g
$99.00
$335.00
$836.00
$2099.00
47
(3)

DAPT is a γ-secretase inhibitor, potentially altering Notch signaling and thereby affecting gene expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is a PI3K inhibitor, which could downregulate AKT/mTOR signaling, potentially leading to reduced protein synthesis and gene expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin can modulate various signaling pathways and potentially affect transcription factors, leading to changes in gene expression.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol has been shown to influence several signaling pathways and might modulate gene expression including that of protocadherins.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

Sulforaphane is known to affect the expression of genes involved in cellular defense mechanisms and may influence other gene expression pathways.