Date published: 2025-12-22

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PCDH10_Pcdh10 Inhibitors

PCDH10 inhibitors belong to a specific category of chemical compounds designed to target and inhibit the activity of the PCDH10 protein, also known as Protocadherin-10. PCDH10 is a member of the protocadherin family of proteins, which are primarily associated with cell-cell adhesion and tissue development. Protocadherins play pivotal roles in establishing and maintaining cell adhesion and are essential for processes such as neuronal connectivity during brain development. PCDH10, specifically, is involved in homophilic cell-cell adhesion, meaning it binds to identical PCDH10 molecules on adjacent cells, contributing to tissue morphogenesis and cellular organization. Inhibitors of PCDH10 are primarily developed for research purposes, serving as valuable tools for scientists and researchers to investigate the molecular mechanisms and functions associated with this protein in the context of cell adhesion and tissue development.

Typically, PCDH10 inhibitors are composed of small molecules or chemical compounds specifically designed to interact with the PCDH10 protein, disrupting its normal function as a cell adhesion molecule. By inhibiting PCDH10, these compounds can potentially interfere with homophilic cell-cell adhesion, leading to alterations in cellular organization and tissue morphogenesis. Researchers use PCDH10 inhibitors in laboratory settings to manipulate the activity of this protein and study its roles in tissue development, neuronal connectivity, and cell adhesion. These inhibitors provide valuable insights into the molecular mechanisms by which PCDH10 influences cell adhesion and contribute to a deeper understanding of its significance in cellular and tissue biology. While PCDH10 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricacies of PCDH10-mediated cell adhesion and its role in developmental processes.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A cytidine analog that incorporates into DNA and RNA, 5-Azacytidine can inhibit DNA methyltransferases, potentially leading to the hypomethylation and subsequent downregulation of gene expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Similar to 5-Azacytidine, Decitabine is used to demethylate DNA and can inhibit gene expression by disrupting DNA methylation patterns.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

This compound is a histone deacetylase inhibitor that changes chromatin structure and can modulate gene expression patterns.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Valproic Acid acts as a histone deacetylase inhibitor, potentially leading to a more relaxed chromatin structure and alteration in gene expression.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Vorinostat inhibits histone deacetylases, affecting gene transcription and potentially reducing expression of certain genes.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

As a histone deacetylase inhibitor, Sodium Butyrate can change the epigenetic marks on histones, thereby affecting gene expression.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

Mithramycin A binds to DNA and inhibits RNA synthesis, which may result in decreased gene expression.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D binds to DNA at the transcription initiation complex, inhibiting RNA polymerase and potentially decreasing gene expression.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

RG108 is a DNA methyltransferase inhibitor that can prevent the methylation of DNA, potentially leading to the downregulation of gene expression.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$206.00
$299.00
$485.00
10
(1)

While primarily known for its role as a PARP inhibitor, Olaparib may also influence gene expression profiles indirectly.