PCDH10 inhibitors belong to a specific category of chemical compounds designed to target and inhibit the activity of the PCDH10 protein, also known as Protocadherin-10. PCDH10 is a member of the protocadherin family of proteins, which are primarily associated with cell-cell adhesion and tissue development. Protocadherins play pivotal roles in establishing and maintaining cell adhesion and are essential for processes such as neuronal connectivity during brain development. PCDH10, specifically, is involved in homophilic cell-cell adhesion, meaning it binds to identical PCDH10 molecules on adjacent cells, contributing to tissue morphogenesis and cellular organization. Inhibitors of PCDH10 are primarily developed for research purposes, serving as valuable tools for scientists and researchers to investigate the molecular mechanisms and functions associated with this protein in the context of cell adhesion and tissue development.
Typically, PCDH10 inhibitors are composed of small molecules or chemical compounds specifically designed to interact with the PCDH10 protein, disrupting its normal function as a cell adhesion molecule. By inhibiting PCDH10, these compounds can potentially interfere with homophilic cell-cell adhesion, leading to alterations in cellular organization and tissue morphogenesis. Researchers use PCDH10 inhibitors in laboratory settings to manipulate the activity of this protein and study its roles in tissue development, neuronal connectivity, and cell adhesion. These inhibitors provide valuable insights into the molecular mechanisms by which PCDH10 influences cell adhesion and contribute to a deeper understanding of its significance in cellular and tissue biology. While PCDH10 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricacies of PCDH10-mediated cell adhesion and its role in developmental processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A cytidine analog that incorporates into DNA and RNA, 5-Azacytidine can inhibit DNA methyltransferases, potentially leading to the hypomethylation and subsequent downregulation of gene expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Similar to 5-Azacytidine, Decitabine is used to demethylate DNA and can inhibit gene expression by disrupting DNA methylation patterns. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This compound is a histone deacetylase inhibitor that changes chromatin structure and can modulate gene expression patterns. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic Acid acts as a histone deacetylase inhibitor, potentially leading to a more relaxed chromatin structure and alteration in gene expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat inhibits histone deacetylases, affecting gene transcription and potentially reducing expression of certain genes. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As a histone deacetylase inhibitor, Sodium Butyrate can change the epigenetic marks on histones, thereby affecting gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to DNA and inhibits RNA synthesis, which may result in decreased gene expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D binds to DNA at the transcription initiation complex, inhibiting RNA polymerase and potentially decreasing gene expression. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
RG108 is a DNA methyltransferase inhibitor that can prevent the methylation of DNA, potentially leading to the downregulation of gene expression. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $206.00 $299.00 $485.00 | 10 | |
While primarily known for its role as a PARP inhibitor, Olaparib may also influence gene expression profiles indirectly. | ||||||