Date published: 2025-10-11

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PAH Antibodies

Santa Cruz Biotechnology delivers a wide array of PAH monoclonal antibodies for studying phenylalanine hydroxylase (PAH) protein. PAH monoclonal antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Phenylalanine hydroxylase is a critical enzyme involved in the metabolism of the amino acid phenylalanine, converting it into tyrosine. This process is essential for the synthesis of neurotransmitters and other important biomolecules. Deficiencies in PAH can lead to phenylketonuria (PKU), a genetic disorder that can result in severe neurological consequences if not managed properly. Understanding the function and regulation of PAH is vital for developing therapeutic strategies for PKU and related metabolic disorders. Research utilizing PAH monoclonal antibodies enables investigation of PAH expression patterns and interactions within cellular pathways. Exploring PAH's role in amino acid metabolism can reveal new insights into metabolic disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies for PAH support researchers worldwide in advancing scientific understanding of metabolic disorders and potential therapeutic approaches.

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PAH Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PAH Antibody (H-2)

sc-271258mouse IgG1 κ404-432 (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(3)

PAH Antibody (E-8)

sc-271257mouse IgG2a κ404-432 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PAH CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAH CRISPR/Cas9 KO Plasmid (h)

sc-404624hGene KnockoutGFP0
(0)

PAH HDR Plasmid (h)

sc-404624-HDRhHomology Directed RepairPuromycin0
(0)

PAH Double Nickase Plasmid (h)

sc-404624-NIChGene KnockoutPuromycin0
(0)

PAH Double Nickase Plasmid (h2)

sc-404624-NIC-2hGene KnockoutPuromycin0
(0)

PAH CRISPR/Cas9 KO Plasmid (m)

sc-422106mGene KnockoutGFP0
(0)

PAH HDR Plasmid (m)

sc-422106-HDRmHomology Directed RepairPuromycin0
(0)

PAH Double Nickase Plasmid (m)

sc-422106-NICmGene KnockoutPuromycin0
(0)

PAH Double Nickase Plasmid (m2)

sc-422106-NIC-2mGene KnockoutPuromycin0
(0)

PAH CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAH CRISPR Activation Plasmid (h)

sc-404624-ACThGene ActivationPuro, Blast, Hygro0
(0)

PAH CRISPR Activation Plasmid (h2)

sc-404624-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PAH Lentiviral Activation Particles (h)

sc-404624-LAChGene ActivationPuro, Blast, Hygro0
(0)

PAH Lentiviral Activation Particles (h2)

sc-404624-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PAH CRISPR Activation Plasmid (m)

sc-422106-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAH CRISPR Activation Plasmid (m2)

sc-422106-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAH Lentiviral Activation Particles (m)

sc-422106-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAH Lentiviral Activation Particles (m2)

sc-422106-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAH siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAH siRNA (h)

sc-41528hGene SilencingN/A0
(0)

PAH shRNA Plasmid (h)

sc-41528-SHhGene SilencingPuromycin0
(0)

PAH shRNA (h) Lentiviral Particles

sc-41528-VhGene SilencingPuromycin0
(0)

PAH siRNA (m)

sc-41529mGene SilencingN/A0
(0)

PAH shRNA Plasmid (m)

sc-41529-SHmGene SilencingPuromycin0
(0)

PAH shRNA (m) Lentiviral Particles

sc-41529-VmGene SilencingPuromycin0
(0)