OTTMUSG00000018998 Activators
The protein "uncharacterized protein LOC333588 isoform X1" (Gm15104) represents an intriguing yet enigmatic element in the biological landscape, presumably involved in significant yet unexplored cellular processes. The specific function of this protein remains undefined due to the lack of direct experimental evidence. The speculative nature of its activation mechanisms underscores a broader challenge in biology: elucidating the roles and activation pathways of poorly characterized proteins. Understanding how LOC333588 isoform X1 is activated requires comprehensive studies involving biochemical assays and in vivo models to map its interactions and effects within the cellular environment.
Hypothesized activation mechanisms for LOC333588 isoform X1 suggest a complex network of cellular signals, primarily mediated by cyclic AMP (cAMP), protein kinase A (PKA), and other secondary messengers. These pathways are central to various cellular processes, implying a significant regulatory role for LOC333588 isoform X1 in cell proliferation, apoptosis, or differentiation. The proposed activators, while not specifically linked to LOC333588 isoform X1 in existing literature, are selected for their established roles in these pathways, offering a theoretical foundation for future experimental investigation. Investigating LOC333588 isoform X1's role within these signaling networks is crucial for a comprehensive understanding of its function and regulation. The activation of LOC333588 isoform X1 by these chemicals remains conjectural, emphasizing the need for targeted research to determine its exact role and biological significance. Such investigations are critical not only for elucidating the function of LOC333588 isoform X1 but also for advancing our understanding of the complex web of cellular signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Epinephrine, through adrenergic receptors, activates adenylate cyclase, increasing cAMP. Elevated cAMP might activate PKA, which could phosphorylate and activate uncharacterized protein LOC333588 isoform X1, implicating it in adrenergic signaling. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX inhibits phosphodiesterases, leading to increased cAMP levels. Higher cAMP can activate PKA, possibly resulting in phosphorylation and activation of uncharacterized protein LOC333588 isoform X1, linking it to cAMP-mediated responses. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
PGE2 activates EP receptors, triggering adenylate cyclase and increasing cAMP. This surge in cAMP could activate PKA, potentially leading to phosphorylation and activation of uncharacterized protein LOC333588 isoform X1, indicating involvement in prostaglandin pathways. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine inhibits phosphodiesterases, raising cAMP levels, potentially enhancing PKA activity. This might facilitate phosphorylation and activation of uncharacterized protein LOC333588 isoform X1, suggesting a role in metabolic regulation and stress response. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram, a PDE4 inhibitor, increases cAMP levels, potentially leading to PKA activation. PKA may then phosphorylate and activate uncharacterized protein LOC333588 isoform X1, implying its role in inflammatory and cognitive pathways. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin activates stress-activated protein kinases, which may indirectly affect uncharacterized protein LOC333588 isoform X1 activity through stress response signaling. | ||||||
Zaprinast (M&B 22948) | 37762-06-4 | sc-201206 sc-201206A | 25 mg 100 mg | $103.00 $245.00 | 8 | |
Zaprinast inhibits PDE5, increasing cGMP levels, which can enhance cAMP pathways, potentially leading to PKA activation and phosphorylation of uncharacterized protein LOC333588 isoform X1, suggesting a role in vascular functions. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
dbcAMP, a cAMP analog, directly activates PKA, possibly leading to phosphorylation and activation of uncharacterized protein LOC333588 isoform X1, emphasizing its role in cAMP-dependent signaling. | ||||||
Milrinone | 78415-72-2 | sc-201193 sc-201193A | 10 mg 50 mg | $162.00 $683.00 | 7 | |
Milrinone inhibits PDE3, increasing cAMP levels and potentially leading to PKA activation. This could result in phosphorylation and activation of uncharacterized protein LOC333588 isoform X1, indicating a role in cardiac function. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, increases cAMP levels, potentially leading to PKA activation and phosphorylation of uncharacterized protein LOC333588 isoform X1, suggesting its involvement in metabolic regulation. | ||||||