OTTMUSG00000005148 Inhibitors
Chemical inhibitors of Uncharacterized protein C7orf57 homolog target various signaling pathways and enzymes that are indirectly associated with the functional role of this protein. These inhibitors primarily focus on disrupting kinase activities and signaling pathways that are essential for the protein's activity in cellular processes. Staurosporine and BMS-354825, as kinase inhibitors, indirectly inhibit the Uncharacterized protein C7orf57 homolog by interfering with phosphorylation processes crucial for its function. This results in a decrease in the protein's activity, impacting cellular mechanisms. Rapamycin, targeting mTOR, alters cell growth conditions, which are essential for the functional expression of the Uncharacterized protein C7orf57 homolog. Similarly, LY294002 and Wortmannin inhibit PI3K, affecting the PI3K-AKT pathway, which plays a vital role in various cellular processes that the protein may influence.
U0126, PD98059, AZD6244, and Trametinib, by inhibiting MEK1/2, impact the MAPK/ERK pathway. This pathway is implicated in a variety of cellular functions, and its disruption can lead to an indirect inhibition of the Uncharacterized protein C7orf57 homolog. SB203580 and SP600125 target the p38 MAP kinase and JNK respectively, both crucial for signaling pathways in which the protein is involved, thus indirectly inhibiting its activity in cellular processes. LY3214996, an ERK1/2 inhibitor, further demonstrates the strategy of targeting upstream signaling molecules to indirectly inhibit the functional role of the Uncharacterized protein C7orf57 homolog in cellular processes. These inhibitors collectively highlight the approach of disrupting key signaling pathways and kinase activities to achieve indirect inhibition of the protein's functional activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine inhibits protein kinases, which can indirectly inhibit Uncharacterized protein C7orf57 homolog by interfering with phosphorylation processes essential for its function. This can lead to a decrease in the protein's activity in cellular processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, a key regulator in cell growth and proliferation. This can indirectly inhibit Uncharacterized protein C7orf57 homolog by altering cellular growth conditions that are essential for the protein's functional expression and activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits PI3K, a crucial kinase in various signaling pathways. This indirect inhibition can affect the Uncharacterized protein C7orf57 homolog by disrupting pathways essential for its functional role in cells. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin, a PI3K inhibitor, can indirectly inhibit Uncharacterized protein C7orf57 homolog by altering the PI3K-AKT pathway, which is essential for various cellular processes that the protein may be involved in. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 inhibits MEK1/2, impacting the MAPK/ERK pathway. This can indirectly inhibit Uncharacterized protein C7orf57 homolog by disrupting signaling pathways crucial for its functional activity in cellular processes. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059, a MEK inhibitor, can indirectly inhibit Uncharacterized protein C7orf57 homolog by altering the MAPK/ERK pathway, which is implicated in various cellular functions that the protein may influence. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAP kinase, potentially affecting pathways in which Uncharacterized protein C7orf57 homolog is involved, thus indirectly inhibiting its functional role in cellular processes. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, which can indirectly inhibit Uncharacterized protein C7orf57 homolog by disrupting JNK signaling pathways crucial for the protein's activity in cellular functions. | ||||||
LY3214996 | 1951483-29-6 | sc-507299 | 5 mg | $265.00 | ||
LY3214996, an ERK1/2 inhibitor, can indirectly inhibit Uncharacterized protein C7orf57 homolog by interfering with the ERK pathway, impacting cellular processes in which the protein is functionally involved. | ||||||
Selumetinib | 606143-52-6 | sc-364613 sc-364613A sc-364613B sc-364613C sc-364613D | 5 mg 10 mg 100 mg 500 mg 1 g | $29.00 $82.00 $420.00 $1897.00 $3021.00 | 5 | |
Selumetinib, a MEK inhibitor, indirectly inhibits Uncharacterized protein C7orf57 homolog by affecting the MAPK/ERK signaling pathway, which may be crucial for the protein's functional activity in cells. | ||||||