otoancorin Inhibitors
Otoancorin inhibitors are a specialized class of compounds that target otoancorin, a protein primarily associated with the inner ear's sensory cells. Otoancorin plays a crucial role in the structural integrity and function of the tectorial membrane, a key component of the cochlear structure involved in sound transduction. By binding to the tectorial membrane, otoancorin contributes to the anchoring and stabilization of this membrane to the underlying hair cells, which are essential for converting sound waves into electrical signals that the brain can interpret. The inhibition of otoancorin offers researchers a unique opportunity to explore the molecular underpinnings of hearing and the specific mechanisms through which this protein influences the auditory process. Through the use of otoancorin inhibitors, scientists can disrupt the normal function of this protein, allowing for a detailed investigation into its role in maintaining the delicate balance of forces within the cochlea and its contribution to auditory signal processing.
In the field of auditory research, otoancorin inhibitors are invaluable tools for studying the biochemistry and biophysics of the inner ear. These inhibitors enable researchers to dissect the interactions between otoancorin and other cochlear proteins, as well as to investigate how alterations in these interactions might affect the overall function of the auditory system. Moreover, otoancorin inhibitors are used in experimental models to assess the impact of reduced otoancorin activity on hearing mechanisms, offering insights into the broader network of proteins that cooperate in the sensory transduction process. By manipulating otoancorin function with specific inhibitors, researchers can uncover the protein's role in cochlear mechanics and its potential involvement in various auditory phenomena. This research is critical for deepening our understanding of the molecular processes that govern hearing, providing a foundation for further exploration into the complex biology of the inner ear.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $165.00 $214.00 $396.00 $617.00 $4804.00 | 19 | |
Marimastat is an MMP inhibitor, impacting matrix remodeling. By altering the extracellular matrix dynamics, it could theoretically affect anchoring proteins like Otoancorin. | ||||||
Cilengitide | 188968-51-6 | sc-507335 | 5 mg | $215.00 | ||
Cilengitide is an integrin antagonist, disrupting cell-matrix interactions. This action could potentially influence the anchoring function of Otoancorin in the inner ear. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Dasatinib inhibits Src kinases, key in cell adhesion and growth. Altered adhesion signaling may indirectly influence proteins associated with cellular anchorage like Otoancorin. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a ROCK inhibitor, impacting cell adhesion mechanisms. This could potentially affect the anchoring or stabilizing role of proteins like Otoancorin in the extracellular matrix. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
SB431542 inhibits TGF-β, a regulator of matrix remodeling. This may indirectly influence the dynamics of proteins that play a role in anchoring within the matrix, like Otoancorin. | ||||||
Vismodegib | 879085-55-9 | sc-396759 sc-396759A | 10 mg 25 mg | $80.00 $96.00 | 1 | |
Vismodegib targets the Hedgehog pathway, crucial for cochlear development. Disruptions could theoretically alter the function or expression of cochlear proteins, including Otoancorin. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
DAPT inhibits the Notch pathway, key in development. This could theoretically impact developmental processes in the cochlea, potentially influencing proteins like Otoancorin. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $35.00 $115.00 $515.00 | 26 | |
XAV939 is a Wnt pathway inhibitor, influencing cell-matrix interactions. Altered Wnt signaling may indirectly impact anchoring proteins or their stabilizing function, including Otoancorin. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $58.00 $170.00 | 15 | |
Nifedipine is a calcium channel blocker. Given calcium's role in adhesion processes, it might indirectly influence the anchoring efficacy of proteins such as Otoancorin. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib inhibits the proteasome, affecting protein turnover. It could influence the stability or turnover rate of anchoring proteins, potentially affecting Otoancorin's function. | ||||||