Date published: 2025-10-18

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Other Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers for use in various applications. Crosslinkers are pivotal in scientific research as they enable the covalent bonding of molecules to study protein interactions, molecular structures, and biochemical pathways. These reagents facilitate the linking of two or more molecules, such as proteins or nucleic acids, which helps in stabilizing complex structures and understanding the spatial arrangement of biological macromolecules. The Other Crosslinkers category encompasses a diverse array of chemical entities designed to create specific and stable covalent bonds between target molecules under various experimental conditions. These compounds are essential in studying protein-protein interactions, mapping binding sites, and elucidating the architecture of macromolecular complexes. By employing these crosslinkers, researchers can capture transient interactions and stabilize delicate structures for analysis using techniques such as mass spectrometry, X-ray crystallography, and nuclear magnetic resonance (NMR) spectroscopy. Furthermore, crosslinkers are instrumental in the development of new materials, as they are used to modify surface properties, create hydrogels, and improve the mechanical strength of polymers. The versatility and specificity of Other Crosslinkers make them invaluable tools for advancing research in structural biology, biochemistry, and materials science. View detailed information on our available Other Crosslinkers by clicking on the product name.

Items 141 to 150 of 214 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-(3-Hydroxypropyl)trifluoroacetamide

78008-15-8sc-253067
500 mg
$148.00
(0)

N-(3-Hydroxypropyl)trifluoroacetamide serves as an effective crosslinker, distinguished by its trifluoroacetyl group, which enhances electrophilicity and promotes rapid reaction kinetics with nucleophiles. This compound's unique molecular structure allows for selective interactions with amines and alcohols, facilitating the formation of robust crosslinked networks. Its hydrophobic trifluoromethyl moiety contributes to improved thermal stability and resistance to environmental degradation, making it suitable for diverse applications.

N-Z-1,6-hexanediamine hydrochloride

78618-06-1sc-253133
1 g
$115.00
(0)

N-Z-1,6-hexanediamine hydrochloride functions as a versatile crosslinker, characterized by its primary amine groups that engage in strong hydrogen bonding and nucleophilic reactions. This compound exhibits a unique ability to form stable covalent bonds with various substrates, enhancing network integrity. Its hydrophilic nature promotes compatibility with aqueous systems, while its chain length contributes to flexibility and mechanical strength in crosslinked materials, optimizing performance in diverse formulations.

4-(2-Chloropropionyl)phenylacetic acid

84098-73-7sc-252079
1 g
$154.00
(0)

4-(2-Chloropropionyl)phenylacetic acid serves as an effective crosslinker, distinguished by its reactive acyl chloride functionality. This compound facilitates rapid acylation reactions, promoting the formation of robust covalent linkages with nucleophilic sites in polymers. Its aromatic structure enhances thermal stability and contributes to the rigidity of crosslinked networks. Additionally, the presence of the chloropropionyl group allows for selective reactivity, enabling tailored modifications in complex formulations.

N-Boc-4-isothiocyanatoaniline

89631-75-4sc-236015
500 mg
$202.00
(0)

N-Boc-4-isothiocyanatoaniline acts as a versatile crosslinker, characterized by its isothiocyanate group, which engages in nucleophilic addition reactions with amines and alcohols. This compound promotes the formation of stable thiourea linkages, enhancing the mechanical properties of polymer matrices. Its Boc (tert-butyloxycarbonyl) protecting group allows for controlled deprotection, enabling sequential functionalization. The unique reactivity and structural features facilitate the design of tailored materials with specific properties.

3-(4-Hydroxymethylphenoxy)propionic acid

101366-61-4sc-251913
1 g
$74.00
(0)

3-(4-Hydroxymethylphenoxy)propionic acid serves as an effective crosslinker, distinguished by its phenolic hydroxymethyl group that enhances hydrogen bonding interactions. This compound promotes the formation of robust ester linkages through its carboxylic acid functionality, facilitating the development of thermally stable networks. Its unique reactivity allows for selective modification, enabling the creation of materials with tailored mechanical and thermal properties, enhancing overall performance in various applications.

2-(Fmoc-amino)ethanol

105496-31-9sc-229861
1 g
$39.00
(0)

2-(Fmoc-amino)ethanol acts as a versatile crosslinker, characterized by its Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which provides steric hindrance and influences reaction kinetics. This compound engages in nucleophilic reactions, allowing for the formation of stable amide bonds. Its unique structure promotes specific molecular interactions, enabling the design of tailored polymer networks with enhanced mechanical integrity and functional properties, suitable for diverse applications.

(p-Azidosalicylamido)ethyl-1,3′-dithiopropionic Acid

107426-70-0sc-212501
10 mg
$300.00
(0)

(p-Azidosalicylamido)ethyl-1,3'-dithiopropionic Acid serves as a distinctive crosslinker, featuring an azide group that facilitates click chemistry reactions, promoting rapid and selective bonding. Its dithiopropionic moiety enhances thiol-ene reactions, leading to robust crosslinked networks. The compound's unique molecular architecture allows for specific interactions with various substrates, influencing the kinetics of polymerization and enabling the creation of tailored materials with improved stability and functionality.

N-Boc-N-methylethylenediamine

121492-06-6sc-255348
1 ml
$310.00
(0)

N-Boc-N-methylethylenediamine acts as a versatile crosslinker, characterized by its ability to form stable amine linkages through nucleophilic reactions. The presence of the Boc protecting group enhances its stability and reactivity, allowing for controlled crosslinking under mild conditions. Its unique structure promotes specific hydrogen bonding interactions, which can influence the mechanical properties of the resulting networks, leading to materials with enhanced resilience and tailored performance characteristics.

N-(5-Hydroxypentyl)trifluoroacetamide

128238-44-8sc-253074
5 ml
$172.00
(0)

N-(2-[(t-Boc)amino]ethyl Maleimide

134272-63-2sc-218906
500 mg
$380.00
(0)

N-(2-[(t-Boc)amino]ethyl Maleimide is a versatile crosslinker characterized by its maleimide functionality, which enables selective thiol-reactive crosslinking. This compound exhibits unique reaction kinetics, allowing for rapid formation of stable covalent bonds under mild conditions. The t-Boc protecting group enhances solubility and stability, facilitating controlled release of the amino group. Its distinct molecular interactions promote the creation of intricate polymer networks, enhancing mechanical properties and resilience.