Date published: 2025-12-16

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ORC CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. ORC gene silencers are available as ORC CRISPR/Cas9 Knockout plasmids and ORC Double Nickase Plasmids. ORC CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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ORC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ORC1 CRISPR/Cas9 KO Plasmid (h)

sc-418358hGene KnockoutGFP0
(0)

ORC1 HDR Plasmid (h)

sc-418358-HDRhHomology Directed RepairPuromycin0
(0)

ORC1 Double Nickase Plasmid (h)

sc-418358-NIChGene KnockoutPuromycin0
(0)

ORC1 Double Nickase Plasmid (h2)

sc-418358-NIC-2hGene KnockoutPuromycin0
(0)

ORC2 CRISPR/Cas9 KO Plasmid (h)

sc-402746hGene KnockoutGFP0
(0)

ORC2 HDR Plasmid (h)

sc-402746-HDRhHomology Directed RepairPuromycin0
(0)

ORC2 Double Nickase Plasmid (h)

sc-402746-NIChGene KnockoutPuromycin0
(0)

ORC2 Double Nickase Plasmid (h2)

sc-402746-NIC-2hGene KnockoutPuromycin0
(0)

ORC3 CRISPR/Cas9 KO Plasmid (h)

sc-405473hGene KnockoutGFP0
(0)

ORC3 HDR Plasmid (h)

sc-405473-HDRhHomology Directed RepairPuromycin0
(0)

ORC3 Double Nickase Plasmid (h)

sc-405473-NIChGene KnockoutPuromycin0
(0)

ORC3 Double Nickase Plasmid (h2)

sc-405473-NIC-2hGene KnockoutPuromycin0
(0)

ORC4 CRISPR/Cas9 KO Plasmid (h)

sc-403634hGene KnockoutGFP0
(0)

ORC4 HDR Plasmid (h)

sc-403634-HDRhHomology Directed RepairPuromycin0
(0)

ORC4 Double Nickase Plasmid (h)

sc-403634-NIChGene KnockoutPuromycin0
(0)

ORC4 Double Nickase Plasmid (h2)

sc-403634-NIC-2hGene KnockoutPuromycin0
(0)

ORC5 CRISPR/Cas9 KO Plasmid (h)

sc-409147hGene KnockoutGFP0
(0)

ORC5 HDR Plasmid (h)

sc-409147-HDRhHomology Directed RepairPuromycin0
(0)

ORC5 Double Nickase Plasmid (h)

sc-409147-NIChGene KnockoutPuromycin0
(0)

ORC5 Double Nickase Plasmid (h2)

sc-409147-NIC-2hGene KnockoutPuromycin0
(0)

ORC6 CRISPR/Cas9 KO Plasmid (h2)

sc-405854-KO-2hGene KnockoutGFP0
(0)

ORC6 HDR Plasmid (h2)

sc-405854-HDR-2hHomology Directed RepairPuromycin0
(0)

ORC6 Double Nickase Plasmid (h)

sc-405854-NIChGene KnockoutPuromycin0
(0)

ORC6 Double Nickase Plasmid (h2)

sc-405854-NIC-2hGene KnockoutPuromycin0
(0)

ORC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ORC1 CRISPR Activation Plasmid (h)

sc-418358-ACThGene ActivationPuro, Blast, Hygro0
(0)

ORC1 CRISPR Activation Plasmid (h2)

sc-418358-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC1 Lentiviral Activation Particles (h)

sc-418358-LAChGene ActivationPuro, Blast, Hygro0
(0)

ORC1 Lentiviral Activation Particles (h2)

sc-418358-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC2 CRISPR Activation Plasmid (h)

sc-402746-ACThGene ActivationPuro, Blast, Hygro0
(0)

ORC2 CRISPR Activation Plasmid (h2)

sc-402746-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC2 Lentiviral Activation Particles (h)

sc-402746-LAChGene ActivationPuro, Blast, Hygro0
(0)

ORC2 Lentiviral Activation Particles (h2)

sc-402746-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC3 CRISPR Activation Plasmid (h)

sc-405473-ACThGene ActivationPuro, Blast, Hygro0
(0)

ORC3 CRISPR Activation Plasmid (h2)

sc-405473-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC3 Lentiviral Activation Particles (h)

sc-405473-LAChGene ActivationPuro, Blast, Hygro0
(0)

ORC3 Lentiviral Activation Particles (h2)

sc-405473-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC4 CRISPR Activation Plasmid (h)

sc-403634-ACThGene ActivationPuro, Blast, Hygro0
(0)

ORC4 CRISPR Activation Plasmid (h2)

sc-403634-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC4 Lentiviral Activation Particles (h)

sc-403634-LAChGene ActivationPuro, Blast, Hygro0
(0)

ORC4 Lentiviral Activation Particles (h2)

sc-403634-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC5 CRISPR Activation Plasmid (h)

sc-409147-ACThGene ActivationPuro, Blast, Hygro0
(0)

ORC5 CRISPR Activation Plasmid (h2)

sc-409147-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC5 Lentiviral Activation Particles (h)

sc-409147-LAChGene ActivationPuro, Blast, Hygro0
(0)

ORC5 Lentiviral Activation Particles (h2)

sc-409147-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC6 CRISPR Activation Plasmid (h)

sc-405854-ACThGene ActivationPuro, Blast, Hygro0
(0)

ORC6 CRISPR Activation Plasmid (h2)

sc-405854-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ORC6 Lentiviral Activation Particles (h)

sc-405854-LAChGene ActivationPuro, Blast, Hygro0
(0)

ORC6 Lentiviral Activation Particles (h2)

sc-405854-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)