OR8G1 Activators
OR8G1 engage the receptor through a sequence of precise molecular interactions. Cyclohexanone, for instance, binds to and stabilizes the open conformation of OR8G1, which is a crucial step in the detection of odorant molecules. This binding facilitates the interaction between the receptor and its associated G proteins, leading to activation. Similarly, Benzaldehyde and Isoamyl acetate serve as odorant molecules that activate OR8G1 by directly binding to its ligand-binding domain. This prompts a conformational transition that underpins the signal transduction process. Eugenol and Limonene also activate OR8G1 through direct interactions with the receptor's binding sites, causing an active receptor conformation and initiating signal transduction through G protein activation.
Methyl salicylate, Ethyl butyrate, Anethole, Citral, Geraniol, and Hexanal each contribute to the activation of OR8G1 by binding to the receptor's ligand-specific domain. This interaction induces a structural change in the receptor, leading to its activation and the commencement of a cascade of signaling events. Alpha-Pinene activates OR8G1 by interacting with the ligand-binding site, which induces a conformational shift, subsequently triggering the activation of the receptor and its signal transduction mechanisms. Each of these chemicals, by binding to the OR8G1 receptor, plays a role in the intricate process of olfactory perception by initiating the necessary changes that allow the receptor to relay the signal downstream.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate serves as an odorant molecule that activates OR8G1 by directly binding to its ligand-binding domain, initiating a conformational transition that activates the receptor's associated G protein, starting the signal transduction process. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol may serve as a direct activator of OR8G1 by interacting with specific binding sites on the receptor, inducing an active receptor conformation and thereby initiating signal transduction through G protein activation. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene can activate OR8G1 by attaching to its odorant-binding site, causing a structural change in the receptor that leads to activation of the G protein signaling pathway. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate might activate OR8G1 by binding to its ligand-specific domain, which leads to a conformational change that triggers the activation of downstream signaling molecules involved in olfactory perception. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate could activate OR8G1 by interacting with the ligand-binding region of the receptor, prompting a conformational shift that leads to the activation of the receptor and its subsequent signaling pathway. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole is capable of activating OR8G1 through direct binding to the receptor's active site, inducing a conformational change that results in the activation of the receptor and engagement of the olfactory signal transduction pathway. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral activates OR8G1 by binding to the receptor's ligand-binding site, causing a conformational alteration that activates the receptor and initiates signal transduction through its associated G protein. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol may activate OR8G1 by binding to the receptor's ligand-specific domain, promoting a change in receptor conformation that leads to the activation of the G protein signaling pathway. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal can activate OR8G1 by directly binding to its ligand-binding domain, causing a conformational change that activates the receptor and initiates downstream signaling involved in the olfactory response. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
Alpha-Pinene might activate OR8G1 by specifically interacting with the receptor's ligand-binding site, triggering a conformational shift that leads to the activation of the receptor and the associated signal transduction mechanisms. | ||||||