OR7D2 Activators
OR7D2 encompass a diverse range of compounds, each capable of binding to this olfactory receptor and initiating a signaling cascade. Isoamyl acetate, with its fruity banana-like aroma, can engage with OR7D2 by docking into the receptor's binding site, triggering a conformational shift that activates the receptor. Similarly, eugenol, a compound with a spicy, clove-like scent, interacts with OR7D2, inducing a series of intracellular signaling events that transmit the scent signal. Benzaldehyde, known for its almond-like fragrance, and methyl salicylate, with a wintergreen odor, both can activate OR7D2 by attaching to the receptor, which launches a G-protein signaling pathway that leads to neuronal depolarization and the perception of their distinct odors.
Geraniol and citronellol, both of which are monoterpenes with floral and rosy scents, respectively, can activate OR7D2 by binding to it, resulting in G-protein-mediated signal transduction. Anethole, with its sweet, licorice-like aroma, and ethylvanillin, reminiscent of vanilla, are also activators of OR7D2. Upon binding, they trigger the receptor to set off a signaling cascade that ultimately translates the chemical stimulus into a distinct olfactory experience. Phenethyl alcohol and linalool, both floral scent components, engage with OR7D2, leading to activation of the associated G-proteins. Finally, alpha-ionone and beta-ionone, which are known for their violet-like and woody fruit scents, respectively, can activate OR7D2. The binding of these compounds to the receptor initiates a cellular response, allowing the scent to be recognized and processed by the olfactory system. Each of these chemicals, by interacting with OR7D2, can induce a nuanced sensory perception, showcasing the intricate nature of scent detection and signaling.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate is known to be a potent odorant for various olfactory receptors, including some in the OR7 family. When binding to OR7D2, this ester would cause a conformational change in the protein, leading to activation of the G-protein-coupled receptor pathway and subsequent cellular responses such as ion channel opening. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol interacts directly with specific olfactory receptors. For OR7D2, eugenol would bind to the ligand-binding domain and activate the receptor, initiating a cascade of intracellular signaling events through the olfactory G-protein pathway, resulting in neuronal depolarization. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate can function as an odorant for several olfactory receptors. Upon binding to OR7D2, it would activate the receptor, initiating a G-protein-mediated signal transduction pathway that results in the opening of ion channels and cellular response to the smell. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol is recognized by various olfactory receptors. It would activate OR7D2 by binding to it, which in turn would activate the associated G-proteins, leading to a signaling cascade that results in olfactory sensory neuron excitation. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol serves as a ligand for multiple olfactory receptors. By binding to OR7D2, citronellol would activate the receptor, leading to the activation of G-protein signaling pathways and subsequent cellular responses, including ion channel modulation and changes in cell polarization. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole is a compound that activates certain olfactory receptors. Binding to OR7D2 would result in receptor activation and the initiation of downstream G-protein-coupled signaling mechanisms, leading to changes in ion channel states and neuronal signaling specific to olfaction. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
Ethylvanillin is known to be an olfactory stimulant. Interaction with OR7D2 would involve direct binding, activating the receptor, and initiating a series of G-protein-coupled intracellular reactions that translate the chemical signal into a nerve impulse related to the perception of smell. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol is a floral-scented compound which can activate certain olfactory receptors. It would activate OR7D2 by binding to its active site, leading to the activation of a G-protein signaling pathway that would ultimately result in the perception of its rose-like fragrance. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool is a terpene alcohol that activates olfactory receptors. Its activation of OR7D2 would occur through direct ligand-receptor interaction, triggering a G-protein-coupled receptor pathway and leading to sensory neuron responses characteristic of smell detection. | ||||||
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
Alpha-ionone is known to trigger responses in olfactory receptors. By binding to OR7D2, alpha-ionone would activate the receptor, which would then initiate the G-protein signaling cascade, resulting in the opening of ion channels and neuronal response. | ||||||