OR4N2 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Icilin | 36945-98-9 | sc-201557 sc-201557A | 10 mg 50 mg | $89.00 $252.00 | 9 | |
This synthetic super-agonist of the transient receptor potential melastatin 8 (TRPM8) channel disrupts the signaling of G-protein-coupled receptors, including OR4N2, by altering ion flow and cellular excitability which indirectly decreases OR4N2 signaling. | ||||||
Capsazepine | 138977-28-3 | sc-201098 sc-201098A | 5 mg 25 mg | $145.00 $450.00 | 11 | |
A selective TRPV1 antagonist, by inhibiting this ion channel, the compound alters the intracellular calcium levels and neural excitability, which can indirectly result in the reduced function of OR4N2 by modulating neuronal signaling. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
As an inhibitor of inositol trisphosphate (IP3) receptors and TRP channels, this compound modulates intracellular calcium signaling, potentially decreasing OR4N2 receptor activity through alterations in cellular signaling cascades. | ||||||
Ruthenium red | 11103-72-3 | sc-202328 sc-202328A | 500 mg 1 g | $184.00 $245.00 | 13 | |
By inhibiting various TRP channels, this polycationic dye affects calcium influx, thereby possibly reducing the activity of OR4N2 by changing the cellular signaling milieu in olfactory sensory neurons. | ||||||
HC-030031 | 349085-38-7 | sc-203994 sc-203994A | 10 mg 50 mg | $87.00 $326.00 | 2 | |
This selective antagonist of the TRPA1 channel can influence nociceptive sensory neurons and indirectly affect OR4N2 by modulating the neuronal environment and intracellular signaling pathways. | ||||||
A-967079 | 1170613-55-4 | sc-363348 sc-363348A sc-363348B | 5 mg 25 mg 100 mg | $86.00 $365.00 $924.00 | 5 | |
A selective antagonist of TRPA1, it may alter the excitability of sensory neurons and indirectly downregulate OR4N2 activity by changing the pattern of neuronal signaling. | ||||||
6-Hydroxydopamine hydrochloride | 28094-15-7 | sc-203482 | 100 mg | $146.00 | 8 | |
By selectively destroying dopaminergic and noradrenergic neurons, this compound can potentially decrease the activity of OR4N2 indirectly by altering neurotransmitter levels and neuronal circuit function. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
A heavy metal salt known to interfere with various calcium channels, potentially leading to the indirect inhibition of OR4N2 by disrupting calcium-dependent signaling within neurons. | ||||||
Tetracaine | 94-24-6 | sc-255645 sc-255645A sc-255645B sc-255645C sc-255645D sc-255645E | 5 g 25 g 100 g 500 g 1 kg 5 kg | $66.00 $309.00 $500.00 $1000.00 $1503.00 $5000.00 | ||
By blocking voltage-gated sodium channels and reducing neuronal excitability, this compound could indirectly decrease the functionality of OR4N2 through dampened neuronal signaling. | ||||||
Methyllycaconitine citrate | 112825-05-5 | sc-253043 sc-253043A | 5 mg 25 mg | $117.00 $398.00 | 2 | |
An antagonist for neuronal alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors, which could lead to a decrease in OR4N2 activity indirectly by modulating cholinergic neurotransmission. | ||||||