Date published: 2025-10-25

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OR2T12 Inhibitors

Chemical inhibitors of Olfactory receptor 2T12 can effectively interfere with the receptor's function through various molecular mechanisms, all converging on the prevention of the receptor's natural activation by odorants. Isopentyl acetate, Hexanal, and Vanillin, for instance, achieve inhibition by competitively binding to the receptor's ligand-binding site. This specific binding prevents the natural odorant molecules from activating Olfactory receptor 2T12, thereby blocking the olfactory signal transduction pathways that are crucial for the receptor's function. Ethyl butyrate and Benzyl alcohol exhibit a similar mechanism of inhibition. They bind to Olfactory receptor 2T12 more effectively than its natural ligands, thereby obstructing the activation by natural odorants and consequently inhibiting the receptor's role in olfactory signal transduction. Additionally, Methyl salicylate, 3-Ethoxy-4-hydroxybenzaldehyde, and Citronellal target Olfactory receptor 2T12 by binding to the receptor's active site. This interaction blocks the receptor's activation by its natural odorants, effectively inhibiting the olfactory signaling processes. Butyl acetate and 2-Phenylethanol inhibit Olfactory receptor 2T12 through a mechanism of competitive inhibition at the receptor's odorant-binding sites, thereby impeding the receptor from contributing to olfactory perception. Lastly, Methyl 2-aminobenzoate and Pentyl acetate inhibit Olfactory receptor 2T12 by preferentially binding to the receptor's active site. This binding impedes the interaction with natural odorant molecules, thereby inhibiting the receptor's crucial function in olfactory signal processing. Through these mechanisms, each chemical specifically targets Olfactory receptor 2T12, preventing its natural activation and thus effectively inhibiting its function in the olfactory signaling pathway.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$105.00
$221.00
(0)

Isopentyl acetate can inhibit Olfactory receptor 2T12 by binding to the receptor's ligand-binding site, preventing the binding of natural odorants and thus inhibiting the receptor's ability to initiate olfactory signal transduction.

Hexanal

66-25-1sc-252885
2 ml
$26.00
(0)

Hexanal can inhibit Olfactory receptor 2T12 through competitive inhibition at the receptor's odorant-binding site, thereby blocking the receptor's natural activation by odorants and inhibiting subsequent olfactory signal transduction pathways.

Vanillin

121-33-5sc-251423
sc-251423A
100 g
500 g
$43.00
$122.00
1
(1)

Vanillin can inhibit Olfactory receptor 2T12 by interacting with the receptor's binding sites, preventing the natural odorant molecules from activating the receptor, and thus inhibiting the receptor's contribution to olfactory signaling.

Ethyl butyrate

105-54-4sc-214986
sc-214986A
1 kg
4 kg
$100.00
$210.00
(0)

Ethyl butyrate can inhibit Olfactory receptor 2T12 by binding to the receptor more strongly than its natural ligands, thus preventing activation by natural odorants and inhibiting the receptor's function in olfactory signal transduction.

Benzyl alcohol

100-51-6sc-326216B
sc-326216
sc-326216A
250 ml
1 L
5 L
$31.00
$102.00
$408.00
(0)

Benzyl alcohol can inhibit Olfactory receptor 2T12 by occupying its binding site, preventing the interaction with natural odorants, and thus inhibiting the receptor's role in the detection of specific scents.

Methyl Salicylate

119-36-8sc-204802
sc-204802A
250 ml
500 ml
$46.00
$69.00
(1)

Methyl salicylate can inhibit Olfactory receptor 2T12 through binding to the receptor's active site, blocking the receptor's activation by natural odorants, and thereby inhibiting olfactory signaling processes.

3-Ethoxy-4-hydroxybenzaldehyde

121-32-4sc-238538
100 g
$31.00
(0)

3-Ethoxy-4-hydroxybenzaldehyde can inhibit Olfactory receptor 2T12 by competitively binding to the receptor's ligand-binding domain, preventing natural odorant interaction and inhibiting the receptor's signaling activity.

(±)-Citronellal

106-23-0sc-234400
100 ml
$51.00
(0)

Citronellal can inhibit Olfactory receptor 2T12 by interacting with key binding sites on the receptor, preventing activation by natural odorants and inhibiting olfactory signal transmission.

Butyl acetate

123-86-4sc-214637
sc-214637A
1 ml
5 ml
$20.00
$77.00
(0)

Butyl acetate can inhibit Olfactory receptor 2T12 by binding to the receptor's odorant-binding site, blocking the interaction with natural ligands, and inhibiting the initiation of olfactory signaling pathways.

2-Phenylethanol

60-12-8sc-238198
250 ml
$68.00
(0)

2-Phenylethanol can inhibit Olfactory receptor 2T12 through competitive inhibition, blocking the receptor's natural odorant binding sites, and thus preventing the receptor from contributing to olfactory perception.