OR2A4 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
α-Ionone inhibits OR2A4 by binding to the same site as its natural odorant ligands, thereby preventing activation of the receptor and subsequent signal transduction. | ||||||
4-Allyl-1,2-dimethoxybenzene | 93-15-2 | sc-232373 sc-232373A sc-232373B | 5 g 25 g 100 g | $24.00 $41.00 $123.00 | ||
4-Allyl-1,2-dimethoxybenzene can inhibit OR2A4 by binding to the ligand-binding site, preventing the protein from undergoing the necessary conformational changes for activation. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamaldehyde can bind to the active site of OR2A4, which blocks the natural ligands from binding and thus inhibits the receptor's function. | ||||||
Thymol | 89-83-8 | sc-215984 sc-215984A | 100 g 500 g | $97.00 $193.00 | 3 | |
Thymol can act on OR2A4 by binding to an allosteric site, which induces a conformational change in the protein, reducing its ability to bind to its natural activating ligands and inhibiting its function. | ||||||
(+)-Carvone | 2244-16-8 | sc-239480 sc-239480A | 5 ml 25 ml | $32.00 $82.00 | 2 | |
Carvone inhibits OR2A4 by competitively binding to its active site, which obstructs the natural ligands' access and prevents the receptor's activation. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol interacts with OR2A4 by binding directly to its active site, which competitively inhibits the binding of natural odorants, thus inhibiting the receptor's activity. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal can inhibit OR2A4 by occupying its ligand-binding site, which prevents the normal activatory conformational changes within the protein structure. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol can bind to the active site of OR2A4, thereby inhibiting the receptor's normal function by blocking the binding of natural activating ligands. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
Limonene can inhibit OR2A4 by binding to the ligand-binding domain, inducing a conformational change which results in an inactive receptor state that cannot be activated by natural ligands. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $62.00 $52.00 | ||
Isoeugenol can bind to the active site of OR2A4, preventing the binding of its natural ligands and therefore inhibiting the protein's activity. | ||||||