Date published: 2026-5-30

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OR11G2 Inhibitors

Chemical inhibitors of the olfactory receptor OR11G2 exert their inhibitory effects through a variety of molecular mechanisms, primarily by competitive binding. These inhibitors are structurally diverse, encompassing ketones, alcohols, esters, and phenolic compounds, which can mimic or compete with the natural ligands of OR11G2. For instance, certain ketone-structured inhibitors can antagonize OR11G2 by binding to the same site on the receptor, leading to desensitization or blocking of the receptor's ability to detect specific scent molecules. Similarly, alcohol-based inhibitors may prevent activation of OR11G2 by occupying the ligand-binding domain, thus acting as competitive inhibitors and preventing the receptor from interacting with its natural odorant molecules. Other inhibitors, such as those found in esters and aldehydes, can bind more strongly to OR11G2 than its natural ligands, thereby functioning as competitive inhibitors. These compounds are found in various natural sources and have distinctive fragrances that include banana, almond, lemon, and cinnamon scents. By occupying the receptor's active site, they preclude the interaction between OR11G2 and its correct ligands, which is essential for the perception of odors. In the case of phenolic inhibitors, they can inhibit the function of OR11G2 by binding to the receptor with higher affinity than the natural odorants, essentially blocking the olfactory signal transduction that would normally be triggered by these ligands.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-Heptanone

110-43-0sc-238060
1 ml
$94.00
(0)

This ketone interacts with specific olfactory receptors, and can act as an antagonist to OR11G2 by binding to the same site or causing receptor desensitization.

1-Octen-3-ol

3391-86-4sc-237604
25 g
$50.00
(0)

An alcohol commonly found in fungi and plants, it can inhibit OR11G2 by competitive binding, preventing the receptor from detecting its specific scent molecules.

Acetophenone

98-86-2sc-239189
5 g
$20.00
(0)

A fragrant compound which can inhibit OR11G2 by binding to the receptors active site and blocking its ability to interact with its natural ligands.

Eugenol

97-53-0sc-203043
sc-203043A
sc-203043B
1 g
100 g
500 g
$32.00
$62.00
$218.00
2
(1)

A phenolic compound that can inhibit OR11G2 function by binding more strongly than the receptor's natural ligands, thus acting as a competitive inhibitor.

Methyl Salicylate

119-36-8sc-204802
sc-204802A
250 ml
500 ml
$47.00
$70.00
(1)

This ester could inhibit OR11G2 by mimicking the receptor's natural ligands and binding to the receptor, preventing activation by the correct ligands.

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$107.00
$225.00
(0)

Known as a banana-scented compound that can inhibit OR11G2 through competitive inhibition, blocking the scent molecules from binding to the receptor.

Citral

5392-40-5sc-252620
1 kg
$212.00
(1)

This compound, with a strong lemon scent, potentially inhibits OR11G2 by binding to the receptor's ligand-binding site, competing with natural aromatic molecules.

D-Limonene

5989-27-5sc-205283
sc-205283A
100 ml
500 ml
$84.00
$129.00
3
(1)

A citrus-scented compound that could inhibit OR11G2 function by binding to the receptor's ligand-binding domain, preventing natural ligand-receptor interactions.

Anisole

100-66-3sc-233877
sc-233877A
500 ml
2.5 L
$65.00
$204.00
(0)

A compound with a sweet odor that might inhibit OR11G2 by occupying the receptors active site, thereby reducing the receptor's ability to bind to its natural ligands.

Geraniol

106-24-1sc-235242
sc-235242A
25 g
100 g
$45.00
$119.00
(0)

Could inhibit OR11G2 by binding to and blocking the receptor's active site, which is necessary for the perception of specific odors.