OR10V1 Activators
OR10V1 include a variety of compounds that are structurally diverse, but all share the ability to bind to the ligand-binding domain of this olfactory receptor, initiating a cascade of intracellular events leading to the perception of odors. Eugenol, for instance, is one such activator that, upon binding to OR10V1, initiates signal transduction pathways integral to smell perception. Citral operates similarly, binding to OR10V1 and causing a conformational change that triggers a G-protein-coupled signal transduction cascade, culminating in olfactory responses. Anethole's structural similarity to other activators enables it to interact with OR10V1, leading to receptor activation and subsequent signaling events.
Isoamyl acetate, with its characteristic fruity odor, activates OR10V1 by binding to its ligand-binding site, which in turn activates the G-protein signaling pathway involved in olfactory detection. In a similar fashion, benzaldehyde and methyl salicylate bind to OR10V1, initiating the G-protein-coupled response and signal transduction involved in scent detection. Geraniol, a terpene, and cinnamaldehyde both activate OR10V1 by binding to its ligand-binding site, initiating a cascade that leads to the perception of odor. Menthol and ethyl vanillin also activate OR10V1 through ligand-receptor binding, setting off the downstream signaling events associated with olfactory perception. Lastly, hexyl acetate and alpha-ionone, by binding to the ligand-binding domain of OR10V1, cause activation of the G-protein-coupled signaling pathways, facilitating the detection of their respective fruity and floral scents.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol has shown activity as an agonist of certain olfactory receptors, including some OR10 family members. The activation of OR10V1 by eugenol leads to the initiation of signal transduction pathways associated with smell perception. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral is a known activator of various olfactory receptors. It activates OR10V1 by binding to the receptor site, initiating a conformational change that triggers a G-protein-coupled signal transduction cascade resulting in olfactory responses. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $565.00 $310.00 | ||
Anethole is structurally similar to known activators of olfactory receptors and can activate OR10V1 by interacting with the ligand-binding domain, leading to receptor activation and subsequent signaling events. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isoamyl acetate, a compound known for its fruity odor, activates OR10V1 by binding to its ligand-binding site, which in turn activates the associated G-protein signaling pathway involved in olfactory detection. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate activates certain olfactory receptors by binding to them, and it can activate OR10V1 by this mechanism, leading to the activation of downstream signaling pathways involved in scent detection. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol is a terpene that activates olfactory receptors by binding to the ligand-binding sites, thereby activating OR10V1 and resulting in the initiation of G-protein-coupled signal transduction pathways. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamaldehyde activates olfactory receptors and would activate OR10V1 by binding to its ligand-binding site, initiating a G-protein-coupled signaling cascade that leads to the perception of odor. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $38.00 $67.00 | ||
Menthol is known to activate certain olfactory receptors and can activate OR10V1 by binding to the receptor, causing a conformational change and initiating the G-protein signaling pathway related to olfactory sensation. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
3-Ethoxy-4-hydroxybenzaldehyde activates olfactory receptors through ligand-receptor binding, and it activates OR10V1 by this direct interaction, which then triggers the downstream signaling events associated with olfactory perception. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, with its fruity odor, activates certain olfactory receptors and would similarly activate OR10V1 by binding to its ligand-binding domain, causing activation of the G-protein-coupled signaling pathways involved in olfaction. | ||||||