Olfr95 Activators
Olfr95 is a member of the olfactory receptor family, serving a crucial role in the human olfactory system by detecting specific odorant molecules. Its activation is a sophisticated process governed by various chemicals, each with distinct mechanisms of action. When an odorant molecule binds to Olfr95, it initiates conformational changes within the receptor, leading to the activation of downstream signaling pathways.
These pathways encompass G-protein-coupled receptor (GPCR) signaling, adenylyl cyclase activation, calcium signaling, and other intracellular events. The chemicals listed in the table above can directly or indirectly activate Olfr95 by modulating these pathways. Some chemicals bind directly to Olfr95's receptor, while others enhance receptor sensitivity or influence downstream components, ultimately leading to functional activation. In conclusion, Olfr95's role in olfaction is essential for our ability to perceive and differentiate various scents. Its activation mechanisms are finely tuned to respond to a wide range of odorant molecules, contributing to our remarkable sense of smell. Understanding these mechanisms enhances our appreciation of olfaction and the intricate molecular processes underlying it.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone activates Olfr95 by binding to its receptor, leading to a conformational change that triggers downstream signaling pathways, ultimately resulting in functional activation. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl acetate activates Olfr95 through the GPCR signaling pathway, where it serves as a ligand, promoting receptor activation and subsequent activation of Olfr95 functionality. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene indirectly activates Olfr95 by promoting the expression of downstream components in its signaling pathway, leading to enhanced receptor activity and functional activation. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal activates Olfr95 by interacting with downstream kinases, phosphorylating key residues, and facilitating receptor activation, ultimately leading to functional activation. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol activates Olfr95 by modulating the concentration of intracellular calcium ions, which plays a crucial role in Olfr95 signaling and its subsequent functional activation. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate activates Olfr95 through the adenylyl cyclase pathway, where it increases cAMP levels, resulting in the activation of Olfr95 and subsequent functional effects. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool activates Olfr95 by binding to a co-receptor and inducing conformational changes in Olfr95, leading to increased receptor activation and functional activation. | ||||||
(−)-trans-Caryophyllene | 87-44-5 | sc-251281 sc-251281A sc-251281B sc-251281C | 1 ml 5 ml 25 ml 1 L | $81.00 $160.00 $446.00 $2918.00 | 1 | |
(-)-trans-Caryophyllene activates Olfr95 by promoting the dimerization of its receptor, a crucial step in initiating downstream signaling events that lead to functional activation. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone activates Olfr95 by directly binding to its receptor and stabilizing an active conformation, resulting in increased receptor activation and subsequent functional activation. | ||||||