Olfr876 Activators
Olfr876, an olfactory receptor gene, plays a pivotal role in the olfactory system, specifically in the perception and discrimination of odorants. As part of the vast family of olfactory receptors, Olfr876 is predominantly expressed in the sensory neurons of the olfactory epithelium within the nasal cavity. Its function is intricately tied to the detection and transduction of odorant molecules, which is a fundamental process in the sense of smell. Activation of Olfr876 is a highly specialized process essential for olfaction. When an odorant molecule, whether it be a naturally occurring compound or a synthetic chemical, interacts with the olfactory receptor, it initiates a cascade of events that culminate in the recognition of a specific scent. The activation process begins with the binding of an odorant molecule to Olfr876, causing a conformational change in the receptor protein. This change in shape is critical, as it triggers the activation of intracellular signaling pathways.
Subsequent to this conformational change, Olfr876 activates a G-protein coupled signaling pathway. The receptor interacts with specific G-proteins, leading to the activation of adenylate cyclase and the subsequent production of cyclic AMP (cAMP) as a second messenger. The rise in cAMP levels results in the activation of protein kinase A (PKA), which phosphorylates various target proteins, including Olfr876 itself. This phosphorylation event is central to Olfr876's activation, as it primes the receptor to transduce the olfactory signal further downstream. The activation of Olfr876 ultimately leads to the generation of action potentials in the olfactory sensory neurons, transmitting the signal to the olfactory bulb in the brain, where odor perception and discrimination occur. In essence, Olfr876 serves as the molecular gateway that allows us to distinguish and perceive the diverse range of odors present in our environment. Its activation mechanism, driven by the binding of odorant molecules and the ensuing intracellular signaling cascades, is a fundamental process underpinning the remarkable sensitivity and specificity of our sense of smell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde activates Olfr876 by binding to its receptor and initiating intracellular signaling events. This binding induces receptor activation, leading to the functional activation of Olfr876 in olfaction. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol directly activates Olfr876 by binding to its receptor, causing receptor activation and subsequent downstream signaling. This activation results in the functional activation of Olfr876 in sensory perception. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl Acetate activates Olfr876 by binding to the receptor associated with the olfactory gene. This interaction leads to receptor activation and downstream signaling, ultimately resulting in the functional activation of Olfr876. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl Salicylate is a specific activator of Olfr876. It interacts with the receptor, inducing a conformational change that activates downstream signaling pathways. This activation leads to the functional activation of Olfr876. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin directly activates Olfr876 by binding to its receptor, triggering receptor activation and subsequent downstream signaling. This activation is responsible for the functional activation of Olfr876 in olfaction. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
Phenethyl Alcohol activates Olfr876 by binding to the olfactory receptor, initiating a conformational change that triggers downstream signaling pathways. This activation leads to the functional activation of Olfr876. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate is a direct activator of Olfr876. It binds to the olfactory receptor, causing receptor activation and subsequent downstream signaling. This activation results in the functional activation of Olfr876 in olfaction. | ||||||
Diallyl sulfide | 592-88-1 | sc-204718 sc-204718A | 25 g 100 g | $42.00 $106.00 | 3 | |
Allyl Sulfide activates Olfr876 by interacting with the receptor associated with the olfactory gene. This interaction induces receptor activation and downstream signaling, leading to the functional activation of Olfr876. | ||||||
4-Methoxybenzaldehyde | 123-11-5 | sc-238884 sc-238884A sc-238884B sc-238884C | 5 g 100 g 250 g 1 kg | $30.00 $42.00 $72.00 $124.00 | ||
4-Methoxybenzaldehyde is a direct activator of Olfr876. It binds to the olfactory receptor, inducing a conformational change that triggers downstream signaling pathways, resulting in the functional activation of Olfr876. | ||||||