Olfr860 Activators
Olfr860 encodes an olfactory receptor protein that is part of the G protein-coupled receptor (GPCR) family. These receptors are crucial for the detection and perception of a wide range of odorant molecules. The activation of Olfr860 involves a highly specific interaction between the receptor and odorant molecules, triggering a cascade of intracellular events that translate these chemical signals into electrical signals for the brain. The specific interaction between Olfr860 and the listed chemicals is a clear demonstration of the lock-and-key mechanism that underlies the sense of smell. Each chemical's unique structure allows it to fit into the active site of Olfr860, leading to receptor activation. This activation process involves a conformational change in the receptor, which, in turn, activates the associated G protein. The activated G protein initiates a series of intracellular signaling pathways, typically involving the production of cyclic AMP (cAMP) and the activation of protein kinase A (PKA). This cascade ultimately results in the generation of nerve impulses that are transmitted to the brain, where they are interpreted as specific odors.
The diverse chemical structures of the activators listed indicate the broad range of molecules that Olfr860 can detect, reflecting the complexity of the olfactory system. These interactions emphasize the receptor's role in discerning a wide array of odors, contributing to the nuanced sensory experience of smell. The direct activation of Olfr860 by these chemicals highlights the importance of structural compatibility in the olfactory system and provides insights into the molecular mechanisms underlying olfaction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate activates Olfr860 by directly binding to its ligand-binding domain, leading to a conformational change in the protein and initiating the olfactory signaling pathway. | ||||||
Heptaldehyde | 111-71-7 | sc-250089 sc-250089A | 2 ml 100 ml | $30.00 $59.00 | ||
Heptaldehyde, an aldehyde with a fruity odor, activates Olfr860 by directly interacting with the receptor, effectively binding to initiate the olfactory signaling cascade. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal, an aldehyde with a citrus-like odor, activates Olfr860 through direct interaction with the receptor site, causing a structural change that leads to the activation of the olfactory signaling pathway. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol, with a floral scent, activates Olfr860 by interacting directly with the receptor, causing a structural change and initiating the olfactory signaling process. | ||||||
Methyl benzoate | 93-58-3 | sc-215338 sc-215338A | 25 g 500 g | $23.00 $33.00 | ||
Methyl benzoate, a benzoate ester, activates Olfr860 by fitting into its binding pocket, leading to a change in the receptor's conformation and triggering the olfactory signaling pathway. | ||||||
Nonanal | 124-19-6 | sc-257926 | 1 g | $67.00 | ||
Nonanal, an aldehyde with a strong citrus scent, activates Olfr860 by directly binding to the receptor's ligand-binding domain, causing a conformational change and initiating the signaling cascade. | ||||||
Decanal | 112-31-2 | sc-234518 | 25 g | $43.00 | ||
Decanal, a long-chain aldehyde, activates Olfr860 through direct binding. Its molecular structure allows effective interaction with the receptor, leading to activation and signal transduction. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, an ester with a fruity odor, activates Olfr860 by directly interacting with its specific binding site on the receptor, initiating a distinct olfactory signal transduction. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol, a terpene alcohol with a floral aroma, activates Olfr860 by binding to the receptor's active site. Its structure allows for effective interaction with the receptor, initiating olfactory signaling. | ||||||
Isovaleric acid | 503-74-2 | sc-250205 | 100 ml | $29.00 | ||
Isovaleric acid, with a pungent odor, activates Olfr860 by binding to the receptor's ligand-binding site, causing a change in the receptor's structure and triggering olfactory signal transduction. | ||||||