Olfr750 is part of the extensive family of olfactory receptors (ORs), specifically classified as a G-protein coupled receptor (GPCR). These receptors are integral to the olfactory system, enabling the detection and differentiation of a wide array of odorant molecules. The specificity of Olfr750 in binding certain odorants is crucial for the system's ability to discriminate between different scents. This receptor, like others in its family, has a unique structure that allows it to selectively interact with particular molecular configurations. This selectivity contributes to the complexity and richness of the human sense of smell.
Upon binding an appropriate odorant molecule, Olfr750 undergoes a conformational change, which is a critical event for its activation. This change in structure activates the associated G-protein, initiating a cascade of intracellular signaling events. These events often involve the production of second messengers, such as cyclic AMP (cAMP), which amplify the signal and lead to a cellular response. This response eventually results in the transmission of a nerve impulse to the brain, interpreted as a distinct odor. The ability of Olfr750 to respond to various chemicals, as listed in the table, highlights its role in the detection of a diverse range of scents. Each chemical's interaction with Olfr750 demonstrates the receptor's ability to specifically bind and respond to different molecular structures, contributing to the nuanced perception of smells. The function of Olfr750 in the olfactory system underscores the complexity of scent detection and the intricate mechanisms by which the olfactory system operates. This process is not only essential for everyday sensory experience but also plays a significant role in behaviors, memories, and emotions associated with different scents.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate, with a banana-like odor, can activate Olfr750 by directly binding to it. This ester induces a conformational change in the receptor, activating the associated G-protein, leading to signaling pathways responsible for the perception of banana-like scents. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate, a compound with a fruity and slightly floral odor, can activate Olfr750. It interacts with the receptor, triggering a conformational change and activating downstream G-protein mediated signaling pathways, essential for the perception of fruity scents. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $30.00 | 1 | |
Benzyl acetate, known for its jasmine-like aroma, can activate Olfr750. Its binding to the receptor causes a conformational change, activating the G-protein, initiating signaling pathways for the perception of jasmine-like aromas. | ||||||
Methyl benzoate | 93-58-3 | sc-215338 sc-215338A | 25 g 500 g | $23.00 $33.00 | ||
Methyl benzoate, with a sweet, floral scent, can activate Olfr750 through direct interaction. Upon binding, it induces a conformational change in the receptor, leading to G-protein activation and signaling pathways for olfactory perception of floral scents. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, present in lavender and other aromatic plants, can activate Olfr750 by binding to the receptor. This interaction induces a conformational change, leading to G-protein activation and signaling pathways crucial for the detection of floral and spicy odors. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, a monoterpenoid and alcohol, can activate Olfr750. By binding to the receptor, geraniol triggers a conformational change, activating downstream G-protein mediated signaling pathways and participating in the olfactory perception process. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol, a constituent of rose and geranium oils, can activate Olfr750 through direct binding. Its interaction with the receptor activates the G-protein, initiating signaling pathways necessary for the perception of floral scents. | ||||||
cis-3,7-Dimethyl-2,6-octadien-1-ol | 106-25-2 | sc-234382 | 5 ml | $51.00 | ||
cis-3,7-Dimethyl-2,6-octadien-1-ol, with a sweet rose-like aroma, can activate Olfr750 by directly interacting with the receptor. This binding induces a conformational change, leading to G-protein activation and signaling pathways important for the perception of rose-like odors. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol, possessing a rose-like scent, can activate Olfr750. Binding to the receptor induces a conformational change, leading to G-protein activation and subsequent signaling pathways for the perception of rose-like odors. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole, a major component of anise and fennel, can activate Olfr750. By binding to the receptor, anethole triggers a conformational change, activating the G-protein and initiating signaling pathways important for perceiving anise-like aromas. | ||||||