Olfr708 Activators
Olfr708, a member of the olfactory receptor gene family, holds a pivotal role in the intricate process of olfaction, the sense of smell. This gene encodes a specialized receptor protein located within the olfactory epithelium, where it serves as a molecular sensor for detecting specific odorant molecules in the surrounding environment. Olfr708's function is vital for our ability to discern a wide array of scents, contributing to our sensory experience and perception of the world. Activation of Olfr708 is a complex but finely tuned process. This receptor becomes operational when it encounters odorant molecules that are structurally compatible with its binding site. Upon binding, these molecules induce conformational changes in Olfr708, initiating a series of intracellular signaling cascades. These signaling pathways include the cAMP, MAPK/ERK, PI3K/Akt, JNK, and calcium pathways, among others. Each of these pathways contributes to the enhancement of Olfr708's functionality in olfactory signal transduction. For instance, activation of the cAMP pathway increases intracellular cAMP levels, heightening the sensitivity to odorants. Simultaneously, the MAPK/ERK pathway influences Olfr708 function, improving the perception of specific odors. The PI3K/Akt and JNK pathways further boost the gene's involvement in odor detection, while calcium signaling plays a critical role in elevating the sensitivity of Olfr708 to odorant stimuli.
In summary, Olfr708's activation is a multifaceted process initiated by the binding of odorant molecules. These molecules induce conformational changes in the receptor, subsequently triggering a variety of intracellular signaling pathways. The orchestration of these pathways collectively enhances Olfr708's function, allowing us to detect and distinguish a broad spectrum of odors in our environment. This molecular intricacy illustrates the remarkable complexity of our sense of smell, and Olfr708's pivotal role within it is a testament to the precision of nature's design.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal acts as a functional activator by binding to Olfr708 and triggering a signal cascade through the cAMP pathway, resulting in increased sensitivity to odorant molecules. This activation enhances olfaction. | ||||||
(−)-Menthol | 2216-51-5 | sc-202705 sc-202705A | 1 g 50 g | $20.00 $41.00 | 2 | |
Menthol serves as a direct activator of Olfr708 by initiating calcium influx, which boosts olfactory signaling. It enhances the protein's functionality in detecting specific odors in the environment. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone activates Olfr708 by stimulating the phospholipase C (PLC) pathway, leading to increased intracellular calcium levels and improved olfactory perception. This functional activation enhances the protein's role in odor detection. | ||||||
(−)-Carvone | 6485-40-1 | sc-293985 sc-293985A | 25 ml 500 ml | $51.00 $230.00 | 2 | |
Carvone influences Olfr708 activity by directly binding to the receptor and facilitating G-protein coupled signaling, resulting in an enhanced response to olfactory stimuli. This activation improves the protein's function in odor detection. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate functions as a direct activator of Olfr708 by enhancing its sensitivity to odorant molecules through the activation of the G-protein signaling pathway. This activation improves the protein's role in olfactory perception. | ||||||
(±)-Methyl Jasmonate | 39924-52-2 | sc-205386 sc-205386A sc-205386B sc-205386C sc-205386D sc-205386E sc-205386F | 1 g 5 g 10 g 50 g 100 g 500 g 1 kg | $36.00 $105.00 $204.00 $890.00 $1671.00 $7081.00 $12491.00 | ||
Methyl Jasmonate activates Olfr708 by binding to its receptor and initiating the JNK signaling pathway, which enhances the gene's involvement in odor detection. This functional activation improves olfaction by increasing the sensitivity of the protein to odorants. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate functions as a direct activator by enhancing Olfr708's sensitivity to odorant molecules through the activation of the cAMP pathway. This activation improves the protein's role in olfactory perception. | ||||||
Isovaleric acid | 503-74-2 | sc-250205 | 100 ml | $29.00 | ||
Isovaleric Acid directly activates Olfr708 by promoting the release of intracellular calcium ions, resulting in improved olfactory signal transduction. It enhances the protein's function in detecting specific odors. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl Acetate serves as a functional activator of Olfr708 by initiating the cGMP signaling pathway, ultimately improving the gene's role in olfactory perception. It directly influences the receptor's activity, enhancing olfaction by increasing the sensitivity of the protein to odorant stimuli. | ||||||