Olfr689 Activators
Olfr689 is a gene encoding an olfactory receptor, which is part of the larger family of G-protein-coupled receptors (GPCRs). These receptors are central to the sense of smell, a crucial sensory modality in many organisms, including humans. The protein Olfr689, produced from this gene, is found in the olfactory epithelium, the specialized tissue in the nose responsible for detecting odors. Olfactory receptors like Olfr689 play a pivotal role in converting chemical signals from odor molecules into electrical signals that the brain interprets as distinct smells. This process is essential for various physiological and behavioral responses, including food selection, danger recognition, and social interactions. The activation mechanism of Olfr689, as with other olfactory receptors, involves the binding of specific odorant molecules. This binding is highly selective, with certain chemical structures fitting into the receptor much like a key fits into a lock. Upon binding of an odorant, Olfr689 undergoes a conformational change. This change is crucial as it leads to the activation of the receptor. Following activation, Olfr689 interacts with a G-protein located inside the cell. The activated G-protein then undergoes a change, leading to the exchange of GDP for GTP on its alpha subunit, which in turn activates further signaling pathways within the cell. These pathways result in the generation of an electrical signal, which is transmitted to the brain for interpretation as a specific odor.
Each olfactory receptor, including Olfr689, is capable of binding to a range of related chemical compounds, which accounts for the ability of the olfactory system to detect and discriminate among a vast array of different odors. This ability to discriminate among different odors is a hallmark of the olfactory system and is crucial for survival and reproduction in many species. Understanding the activation and function of olfactory receptors such as Olfr689 is fundamental not only to our knowledge of sensory biology but also for potential applications in various fields. These include the development of artificial noses for environmental monitoring, the creation of novel fragrances and flavors, and potentially even in medical diagnostics. The study of olfactory receptors, their activation mechanisms, and their interactions with odorants provides valuable insights into the complex and nuanced nature of smell, a sense that is integral to the experience of the world around us.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate can activate Olfr689 by binding to its specific olfactory receptor site, triggering a conformational change in the receptor. This change leads to the activation of associated G-proteins and the initiation of olfactory signal transduction pathways. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, through its interaction with Olfr689, can activate the receptor by directly binding to it. This binding induces a conformational change in Olfr689, enabling the activation of G-protein signaling pathways integral to the olfactory signal transduction process. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate can activate Olfr689 by binding to the receptor's specific site. This interaction triggers a conformational alteration in Olfr689, facilitating the activation of downstream G-protein mediated signaling mechanisms involved in olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate can activate Olfr689 by interacting with its sensory domain. This binding facilitates the activation of the receptor, promoting the initiation of G-protein coupled intracellular signaling pathways involved in the perception of olfactory cues. | ||||||
Benzyl alcohol | 100-51-6 | sc-326216B sc-326216 sc-326216A | 250 ml 1 L 5 L | $32.00 $104.00 $416.00 | ||
Benzyl alcohol can activate Olfr689 through its interaction with the receptor's binding site. This binding promotes a change in receptor conformation, enabling the activation of associated G-protein signaling pathways, critical for olfactory signal transduction. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate can activate Olfr689 by binding to its ligand-specific site. This interaction induces a receptor conformational change, leading to the activation of G-protein mediated signaling pathways involved in olfactory perception. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, by interacting with Olfr689, can activate the receptor through direct binding. This interaction induces a conformational change, leading to the activation of G-protein signaling pathways integral to the olfactory signal transduction process. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool can activate Olfr689 through binding to the receptor's specific site. This interaction triggers a conformational alteration of Olfr689, facilitating the activation of downstream G-protein mediated signaling mechanisms involved in olfactory perception. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol can activate Olfr689 by binding to its sensory domain. This binding facilitates the activation of the receptor, promoting the initiation of G-protein coupled intracellular signaling pathways involved in the perception of olfactory cues. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
Alpha-Pinene can activate Olfr689 through its interaction with the receptor's binding site. This binding promotes a change in receptor conformation, enabling the activation of associated G-protein signaling pathways, critical for olfactory signal transduction. | ||||||