Olfr686 Activators
Olfr686 is a gene that encodes for an olfactory receptor, which is a part of the extensive and diverse family of G-protein-coupled receptors (GPCRs). These receptors are pivotal in the sense of smell, a key sensory modality in many organisms, including humans. The protein product of Olfr686, located in the olfactory epithelium, is responsible for detecting specific odorant molecules and converting these chemical signals into electrical signals that the brain interprets as distinct smells. This conversion from chemical to electrical signal is essential for the perception of odors and plays a significant role in various behaviors and physiological responses. The activation of Olfr686 follows a specific and intricate mechanism, characteristic of olfactory receptors. When an odorant molecule, with a structure complementary to the receptor, binds to Olfr686, it induces a conformational change in the receptor. This change is the initial step in the receptor's activation. Once activated, Olfr686 interacts with an intracellular G-protein, triggering a series of biochemical reactions. The G-protein, upon activation, undergoes a change that involves the exchange of GDP for GTP on its alpha subunit. This exchange activates further signaling pathways inside the cell, leading to the production of an electrical signal. This electrical signal is then conveyed to the brain, where it is processed and perceived as a specific odor.
Each olfactory receptor, including Olfr686, is capable of binding to multiple related chemical compounds, which allows the olfactory system to detect and distinguish among a vast array of odors. This ability to discriminate among different odors is a hallmark of the olfactory system and is crucial for survival and reproduction in many species. The understanding of how receptors like Olfr686 are activated by specific chemicals is not only fundamental to our knowledge of sensory biology but also has potential applications in various fields, including flavor and fragrance development, environmental monitoring, and even in the design of biosensors. The study of olfactory receptors, their activation mechanisms, and their interactions with odorants provides valuable insights into the complex and nuanced nature of smell, a sense that is integral to the experience of the world around us.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate can activate Olfr686 by binding to its specific olfactory receptor site, which triggers a conformational change in the receptor. This change leads to the activation of associated G-proteins and the initiation of olfactory signal transduction pathways. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, through its interaction with Olfr686, can activate the receptor by directly binding to it. This binding induces a conformational change in Olfr686, enabling the activation of G-protein signaling pathways integral to the olfactory signal transduction process. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate can activate Olfr686 by binding to the receptor's specific site. This interaction triggers a conformational alteration in Olfr686, facilitating the activation of downstream G-protein mediated signaling mechanisms involved in olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate can activate Olfr686 by interacting with its sensory domain. This binding facilitates the activation of the receptor, promoting the initiation of G-protein coupled intracellular signaling pathways involved in the perception of olfactory cues. | ||||||
Benzyl alcohol | 100-51-6 | sc-326216B sc-326216 sc-326216A | 250 ml 1 L 5 L | $32.00 $104.00 $416.00 | ||
Benzyl alcohol can activate Olfr686 through its interaction with the receptor's binding site. This binding promotes a change in receptor conformation, enabling the activation of associated G-protein signaling pathways, critical for olfactory signal transduction. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate can activate Olfr686 by binding to its ligand-specific site. This interaction induces a receptor conformational change, leading to the activation of G-protein mediated signaling pathways involved in olfactory perception. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, by interacting with Olfr686, can activate the receptor through direct binding. This interaction induces a conformational change, leading to the activation of G-protein signaling pathways integral to the olfactory signal transduction process. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool can activate Olfr686 through binding to the receptor's specific site. This interaction triggers a conformational alteration of Olfr686, facilitating the activation of downstream G-protein mediated signaling mechanisms involved in olfactory perception. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol can activate Olfr686 by binding to its sensory domain. This binding facilitates the activation of the receptor, promoting the initiation of G-protein coupled intracellular signaling pathways involved in the perception of olfactory cues. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
Alpha-Pinene can activate Olfr686 through its interaction with the receptor's binding site. This binding promotes a change in receptor conformation, enabling the activation of associated G-protein signaling pathways, critical for olfactory signal transduction. | ||||||