Olfr668 Activators
Olfr668 is an integral part of the G protein-coupled receptor (GPCR) family, specifically categorized as an olfactory receptor. It plays a pivotal role in the sense of smell, a vital sensory modality for various physiological and behavioral processes. Olfr668's primary function is to detect and discriminate a wide array of odorant molecules, converting these chemical stimuli into neural signals that are processed as distinct smells in the brain.
The activation mechanism of Olfr668 follows a highly specific and intricate biochemical pathway. When an odorant molecule binds to Olfr668, it induces a critical conformational change in the receptor. This structural alteration is the foundational step for receptor activation. It enables the interaction of Olfr668 with intracellular G proteins, which upon activation, undergo subunit dissociation and engage with downstream signaling components. These interactions result in the production of secondary messengers that amplify the initial signal, ultimately leading to a cellular response. For olfactory receptors like Olfr668, this response is typically the generation of an electrical signal in olfactory sensory neurons, which is then relayed to the brain and perceived as a specific odor. The chemicals listed in the table have been identified as potential activators of Olfr668 based on their molecular structures and their ability to effectively bind and activate the receptor. These interactions are hypothesized to induce the necessary conformational changes in Olfr668, triggering the GPCR signaling cascade essential for olfactory signal transduction. Understanding the activation of Olfr668 by these chemicals provides critical insights into the molecular mechanisms of olfaction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol activates Olfr668 by binding to its ligand-binding domain, inducing a conformational change, and triggering the GPCR signaling pathway for olfactory signal transduction. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin activates Olfr668 through direct interaction with the ligand-binding site, causing a structural change that leads to GPCR-mediated signal transduction related to olfaction. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate activates Olfr668 by binding to the receptor, mimicking natural ligands, and initiating the GPCR cascade for olfactory signal propagation. | ||||||
Dipentene | 138-86-3 | sc-252747 | 4 L | $120.00 | ||
Dipentene activates Olfr668 by binding to its ligand-binding domain, leading to a structural change in the receptor and activation of the GPCR pathway for olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate activates Olfr668 by interacting with the ligand-binding domain, causing a conformational change and initiating the GPCR pathway for olfactory signal transduction. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol activates Olfr668 by binding to specific receptor sites, leading to a conformational change and the activation of G protein-mediated signal transduction for smell perception. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $27.00 | 1 | |
trans-Anethole activates Olfr668 by interacting with its ligand-binding domain, inducing a structural change and activating the GPCR signaling pathway for olfactory signal propagation. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Olfr668 by binding to the ligand-binding domain, causing a structural change and activating the GPCR pathway for olfactory signal transmission. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamaldehyde activates Olfr668 by direct interaction with the receptor, binding to the ligand-binding domain, and inducing a conformational change that triggers G protein-mediated signaling. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
Alpha-Pinene activates Olfr668 by binding to its ligand-binding domain, causing a structural change in the receptor, and initiating the GPCR-mediated signaling pathway for olfactory signal transduction. | ||||||