Olfr550 Activators
Chemical activators of Olfr550 are selected based on their potential to directly activate the protein through interactions with its ligand-binding domains or allosteric sites. These chemicals, including eugenol, citral, anethole, isoamyl acetate, menthol, vanillin, ethyl butyrate, benzaldehyde, cinnamaldehyde, geraniol, alpha-pinene, and linalool, represent a diverse range of compounds that can activate Olfr550. Each of these chemicals possesses distinct molecular features that could facilitate their interaction with Olfr550. For instance, eugenol, with its phenolic structure, might fit into the binding pocket of Olfr550, mimicking the action of natural ligands. Similarly, citral's aldehyde group could interact with specific amino acids in the receptor's binding domain, inducing a conformational change that activates the receptor. Anethole's similarity to natural aromatic ligands could enable it to bind and activate Olfr550, initiating the olfactory signal transduction. Isoamyl acetate, with its ester functional group, may have a structural affinity for Olfr550, leading to its activation. Menthol, known for its cooling effect, might activate the receptor through a unique mechanism involving allosteric modulation. Vanillin's vanilloid structure could interact with the receptor's binding sites, leading to activation and signal propagation.
Ethyl butyrate's fruity odor and molecular structure might facilitate its binding to Olfr550, activating the receptor. Benzaldehyde, with its almond-like scent, could mimic natural aromatic ligands of Olfr550, leading to receptor activation. Cinnamaldehyde's structure might allow it to interact with specific binding sites on Olfr550, activating the receptor and initiating olfactory signaling. Geraniol, a terpene alcohol, could activate Olfr550 by binding to the receptor. Alpha-pinene's terpene structure might facilitate its interaction with the receptor's binding sites, leading to activation. Linalool, with its floral scent, could activate Olfr550 by interacting with its ligand-binding sites, triggering a conformational change and subsequent receptor activation. In summary, these chemicals have been selected for their potential to interact with and activate Olfr550 through direct binding or allosteric modulation, leading to the initiation of olfactory signal transduction pathways. This diverse range of compounds offers various mechanisms for potentially activating the protein encoded by the Olfr550 gene.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, a phenolic compound, is known to bind to and activate certain olfactory receptors. For Olfr550, it could directly activate the protein by binding to its specific site, triggering a conformational change that results in signal transduction across the olfactory neuron membrane. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, an aldehyde with a strong lemon odor, could interact with Olfr550 by binding to its ligand-binding domain. This interaction may lead to the activation of the receptor, initiating a G-protein-coupled signal transduction pathway commonly seen in olfactory receptors. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $28.00 | 1 | |
trans-Anethole, a compound found in anise, may activate Olfr550 by mimicking the structure of its natural ligand. This structural similarity could enable anethole to bind and activate the receptor, leading to the initiation of olfactory signaling cascades. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Known for its banana-like odor, Isopentyl acetate could activate Olfr550 by binding to its external domain. This interaction would induce the receptor's activation, leading to the propagation of olfactory signals within the neuron. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $39.00 $68.00 | ||
Menthol, a compound with a cooling sensation, might activate Olfr550 through a non-traditional binding mechanism. This could involve allosteric modulation of the receptor, resulting in its activation and subsequent signal transduction. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin, a primary component of vanilla bean extract, could activate Olfr550 by binding to specific sites on the receptor. This binding may trigger a conformational change, leading to the activation of the G-protein-coupled signaling pathway. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, with a fruity odor, may activate Olfr550 through direct interaction with the receptor's ligand-binding domain, initiating signal transduction pathways specific to olfactory receptors. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde, known for its cinnamon odor, might activate Olfr550 by interacting with specific binding sites on the receptor, leading to activation and subsequent olfactory signaling. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, a terpene alcohol with a sweet rose-like odor, could activate Olfr550 by directly binding to it. This interaction would trigger the receptor's activation and initiate olfactory signal transduction pathways. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
Alpha-pinene, a terpene with a pine-like aroma, might activate Olfr550 through direct interaction with its ligand-binding domain, leading to receptor activation and signal transduction within olfactory neurons. | ||||||