Chemical activators of Olfr504, as proposed in the table, are based on the typical mechanisms of olfactory receptor activation. These include Limonene, Benzaldehyde, and Pinene, which are theorized to directly interact with Olfr504. Upon binding, these compounds likely induce a conformational change in the receptor, leading to activation of the G-protein-coupled receptor (GPCR) signaling pathway. This process usually results in the production of cyclic AMP, a crucial second messenger in olfactory signal transduction.
Other compounds, such as Geraniol, Citronellol, and Eugenol, are also postulated to function similarly by binding to Olfr504 and activating the GPCR pathway. Each of these chemicals has distinct molecular structures that allow for specific interactions with Olfr504, triggering receptor activation. This specificity is key to the diverse range of odor detection and recognition in the olfactory system. The proposed activation of Olfr504 by these chemicals highlights the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
D-Limonene, with its citrusy aroma, may activate Olfr504 by binding to its ligand-binding domain, initiating GPCR signaling, leading to increased intracellular cyclic AMP, crucial for olfactory signal transduction. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
(-)-α-Pinene, characterized by its pine scent, might activate Olfr504 by interacting with its active site, triggering GPCR-mediated signaling pathways and resulting in an elevation of cyclic AMP levels. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, with its floral aroma, could activate Olfr504 by binding to its ligand-binding site, initiating GPCR signaling and leading to increased cyclic AMP production, essential for olfactory signal processing. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
(±)-β-Citronellol, known for its rose-like scent, might activate Olfr504 through direct receptor interaction, leading to GPCR activation and a subsequent increase in cyclic AMP, crucial for olfactory signal transduction. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, characterized by its spicy clove aroma, may activate Olfr504 by binding to its active site, triggering GPCR signaling pathways, and increasing cyclic AMP levels, vital for olfactory signal transduction. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate, with its banana-like scent, could activate Olfr504 by directly interacting with the receptor, leading to GPCR activation and subsequent cyclic AMP elevation, crucial for olfactory signal processing. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin, known for its vanilla aroma, might activate Olfr504 by binding to its ligand-binding domain, triggering GPCR-mediated signaling and an increase in cyclic AMP. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $28.00 | 1 | |
trans-Anethole, characterized by its licorice scent, could activate Olfr504 through direct receptor interaction, initiating GPCR signaling and resulting in elevated cyclic AMP levels, essential for olfactory signal processing. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde, with its cinnamon aroma, may bind to Olfr504, activating the receptor and initiating GPCR signaling, resulting in increased cyclic AMP levels, vital for olfactory signal transduction. | ||||||
Thymol | 89-83-8 | sc-215984 sc-215984A | 100 g 500 g | $97.00 $193.00 | 3 | |
Thymol, known for its thyme-like scent, might activate Olfr504 by interacting with its active site, initiating GPCR signaling and leading to increased cyclic AMP production. | ||||||