Chemical activators of Olfr498, as proposed in this list, are based on typical activation mechanisms of olfactory receptors. These chemicals, such as Ethyl hexanoate, Linalool, and Geraniol, are hypothesized to interact directly with Olfr498, a G-protein-coupled receptor (GPCR). Upon binding to Olfr498, these compounds likely induce a conformational change in the receptor, initiating a cascade of intracellular events characteristic of GPCR activation. This process typically results in the production of cyclic AMP, a critical second messenger in olfactory signal transduction. The elevation in cyclic AMP is essential for converting the chemical signal into a neural signal, facilitating olfactory perception.
Other compounds like Citronellol, Eugenol, and Nerol are also hypothesized to function similarly, binding to Olfr498 and activating the GPCR pathway. Each of these chemicals has a unique molecular structure that allows specific interaction with Olfr498, triggering the receptor's activation. This specificity is vital for the diverse range of odor detection and recognition in the olfactory system. The proposed activation of Olfr498 by these chemicals underscores the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate, with its fruity aroma, may bind to Olfr498, activating the receptor through G protein-coupled receptor (GPCR) pathways, which lead to increased intracellular cyclic AMP levels, a crucial component for olfactory signal transduction. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, known for its floral scent, might activate Olfr498 by directly interacting with the receptor, leading to GPCR activation and subsequent elevation of cyclic AMP levels, essential for olfactory signaling. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, with a rose-like aroma, could interact with Olfr498, stimulating the receptor through GPCR pathways, resulting in increased cyclic AMP production, crucial for olfactory signal processing. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
(±)-β-Citronellol, characterized by its citrusy scent, may activate Olfr498 by binding to its active site, triggering GPCR signaling, and leading to an increase in cyclic AMP, vital for olfactory signal transduction. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, with a clove-like aroma, might activate Olfr498 through direct receptor interaction, initiating GPCR pathway activation and an increase in cyclic AMP levels, necessary for olfactory signal processing. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, characterized by its lemon scent, may bind to Olfr498, activating the receptor and leading to GPCR pathway initiation, resulting in increased cyclic AMP, vital for olfactory signal processing. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol, with a rose-like aroma, could activate Olfr498 through direct binding, triggering a cascade of intracellular events typical of GPCR activation, including increased cyclic AMP, necessary for olfactory signaling. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, known for its fruity and floral scent, may activate Olfr498 by directly interacting with the receptor, inducing the GPCR pathway and resulting in elevated cyclic AMP, crucial for olfactory signaling. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $63.00 $53.00 | ||
Isoeugenol, with a clove-like aroma, could bind to Olfr498, activating the receptor and initiating the GPCR signaling cascade, leading to increased cyclic AMP levels, essential for olfactory signal transduction. | ||||||
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
Alpha-ionone, characterized by its violet-like scent, might activate Olfr498 through direct receptor interaction, leading to GPCR activation and a subsequent increase in cyclic AMP levels, crucial for olfactory signal processing. | ||||||