Olfr495 Activators
Chemical activators of Olfr495, as proposed in this list, are based on the typical activation mechanisms of olfactory receptors. These chemicals, such as Linalool, Citral, and Limonene, are hypothesized to interact directly with Olfr495, a G-protein-coupled receptor (GPCR). Upon binding to Olfr495, these compounds are likely to induce a conformational change in the receptor, initiating a cascade of intracellular events characteristic of GPCR activation. This process typically results in the production of cyclic AMP, a critical second messenger in olfactory signal transduction. The elevation in cyclic AMP is essential for converting the chemical signal into a neural signal, facilitating olfactory perception.
Other compounds like Eugenol, Geraniol, and α-Pinene are also hypothesized to function similarly, binding to Olfr495 and activating the GPCR pathway. Each of these chemicals has a unique molecular structure that allows specific interaction with Olfr495, triggering the receptor's activation. This specificity is vital for the diverse range of odor detection and recognition in the olfactory system. The proposed activation of Olfr495 by these chemicals underscores the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, a floral scented compound, may activate Olfr495 by directly interacting with the receptor's binding site, inducing conformational changes that trigger the GPCR signaling pathway and result in increased cyclic AMP levels, essential for olfactory signal transduction. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, known for its lemon-like aroma, could bind to Olfr495, activating the receptor through the GPCR pathway and leading to an elevation in cyclic AMP, crucial for olfactory signal processing. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
D-Limonene, with a citrus scent, might activate Olfr495 through direct interaction, triggering a cascade of intracellular events typical of GPCR activation, including increased cyclic AMP, essential for olfactory signaling. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, characterized by a spicy, clove-like aroma, could activate Olfr495 by directly binding to the receptor, leading to GPCR pathway activation and subsequent increase in cyclic AMP, crucial for olfactory signal transmission. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, with a sweet, floral scent, may activate Olfr495 through direct binding, initiating the GPCR signaling pathway and resulting in increased cyclic AMP levels, important for olfactory signal transduction. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene, known for its pine-like aroma, might activate Olfr495 by interacting with its ligand-binding domain, triggering the GPCR mechanism and elevating cyclic AMP levels, crucial for olfactory signal transduction. | ||||||
(−)-trans-Caryophyllene | 87-44-5 | sc-251281 sc-251281A sc-251281B sc-251281C | 1 ml 5 ml 25 ml 1 L | $81.00 $160.00 $446.00 $2918.00 | 1 | |
(-)-trans-Caryophyllene, with a woody, spicy aroma, could bind to Olfr495, activating the receptor and leading to GPCR pathway initiation, resulting in increased cyclic AMP, essential for olfactory signal processing. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol, characterized by a rose-like scent, might activate Olfr495 through direct receptor interaction, leading to GPCR activation and a rise in cyclic AMP levels, essential for olfactory signal processing. | ||||||
Thymol | 89-83-8 | sc-215984 sc-215984A | 100 g 500 g | $97.00 $193.00 | 3 | |
Thymol, known for its thyme-like scent, could bind to Olfr495, activating the receptor and initiating the GPCR signaling cascade, leading to increased cyclic AMP levels, essential for olfactory signal transduction. | ||||||