Chemical activators of Olfr448 play a pivotal role in the sensory perception of a variety of aliphatic aldehyde odors. Butyl Acetate and Ethyl Hexanoate, for example, bind to Olfr448, triggering a conformational change that activates the G-protein coupled receptor. This activation leads to a signaling cascade within the olfactory sensory neurons, enhancing the perception of odors characteristic of these esters. Amyl Acetate and Hexyl Acetate function as agonists, inducing structural changes in Olfr448 and initiating downstream events that amplify the olfactory signal.
Furthermore, Octyl Acetate, Nonanal, and Decanal interact directly with Olfr448, activating the receptor and triggering G-protein coupled signaling mechanisms. This enhances the perception of odors associated with these compounds. Dodecanal, Tridecanal, Tetradecanal, Pentadecanal, and Hexadecanal also contribute significantly. They bind to Olfr448 and initiate a signaling cascade that results in an enhanced perception of their related odors. These aldehydes, through their specific interactions with Olfr448, effectively activate the olfactory receptor, leading to an enhanced sensory experience of a diverse array of aliphatic aldehyde odors. Their ability to bind and activate Olfr448 plays a crucial role in the functional activation of this olfactory receptor, contributing to the complex and nuanced nature of olfactory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Propyl acetate | 109-60-4 | sc-250792 | 500 ml | $20.00 | ||
Propyl Acetate activates Olfr449 by binding to its specific receptor site. This binding triggers a conformational change in the receptor, leading to the activation of the associated G-protein. This activation initiates a signaling cascade within olfactory sensory neurons, directly enhancing the perception of odors characteristic of Propyl Acetate. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl Salicylate functions as an agonist to Olfr449. Its binding induces a structural change in the receptor, enabling G-protein activation. This initiates a series of downstream events that amplify the olfactory signal, enhancing the sensory response to Methyl Salicylate. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl Acetate specifically binds to Olfr449, triggering the activation of the G-protein coupled receptor. This interaction enhances olfactory signal transduction, leading to an increased perception of Isopentyl Acetate-related odors. | ||||||
Ethyl propionate | 105-37-3 | sc-214997 sc-214997A | 25 ml 500 ml | $15.00 $40.00 | ||
Ethyl Propionate activates Olfr449 by binding to the receptor, causing a conformational change that initiates G-protein activation. This leads to a cascade of intracellular events, increasing sensory response to odors similar to Ethyl Propionate. | ||||||
Butyl butyrate | 109-21-7 | sc-239439 | 250 ml | $210.00 | ||
Butyl Butyrate directly interacts with Olfr449 as an agonist. This binding triggers the receptor's G-protein coupled signaling mechanism, enhancing the sensory perception of Butyl Butyrate-associated odors. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate activates Olfr449 by binding to its receptor site, initiating the activation of the associated G-protein and leading to a signaling cascade that amplifies olfactory signal transduction for Ethyl Caproate. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl Acetate, upon binding to Olfr449, activates the G-protein coupled receptor mechanism. This interaction results in enhanced perception of smell, particularly for odors similar to Hexyl Acetate. | ||||||
Isopentyl butyrate | 106-27-4 | sc-269267 | 100 g | $67.00 | ||
Isopentyl butyrate engages Olfr449 as an agonist, inducing a change in the receptor's structure and activating the G-protein. This leads to downstream events that amplify the olfactory signal, enhancing sensory response to Isoamyl Butyrate. | ||||||
Benzyl alcohol | 100-51-6 | sc-326216B sc-326216 sc-326216A | 250 ml 1 L 5 L | $32.00 $104.00 $416.00 | ||
Benzyl Alcohol interacts with Olfr449, activating the receptor and leading to a series of intracellular events that culminate in an increased sensory response to Benzyl Alcohol and similar odorants. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl Acetate binds and activates Olfr449, initiating a G-protein coupled receptor signaling cascade. This leads to an increased intracellular calcium level, enhancing the sensory perception of Ethyl Acetate and related odors. | ||||||