Chemical activators of Olfr426 engage with the protein through direct interactions that lead to its functional activation. Isoamyl acetate, for instance, binds to the ligand-binding domain of Olfr426, causing a conformational change that is essential for the initiation of the olfactory signaling cascade. Similarly, benzaldehyde and eugenol activate Olfr426 by interacting with specific sites on the protein, facilitating structural alterations that trigger the olfactory signal transduction process. Methyl salicylate, limonene, and phenethyl alcohol also act as activators by binding to the extracellular domain of Olfr426. This binding induces changes in the protein's configuration that are critical for the activation of olfactory signaling mechanisms. These activators are adept at fitting into the Olfr426 ligand-binding pocket, inducing the necessary structural changes to activate the olfactory signaling pathway.
Other chemicals, such as geraniol, vanillin, and hexanal, have a similar impact on Olfr426, where their binding promotes a conformational shift, activating the olfactory signal transduction. The monoterpene compounds α-pinene and β-pinene also play a role in the activation of Olfr426 by directly interacting with the protein's ligand-binding domain. This interaction causes a conformational shift that is pivotal for the activation of the protein and the subsequent olfactory signaling pathways. Each of these chemicals has a unique molecular structure that allows them to bind effectively to Olfr426 and initiate a cascade of biochemical events leading to the protein's activation. Through these direct interactions, these diverse chemical activators are essential in modulating the functional response of Olfr426, highlighting their importance in the precise activation of olfactory signaling.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate directly activates Olfr426 by binding to its ligand-binding domain, inducing a conformational change that leads to the activation of the protein and the initiation of the olfactory signaling cascade. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol initiates Olfr426 activation via direct binding to the receptor, causing a change in its structure that results in the activation of the olfactory transduction pathway. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates Olfr426 by binding to its extracellular domain, which triggers a change in the protein's configuration, leading to the activation of the olfactory signaling mechanisms. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral engages with Olfr426 by binding directly to the ligand-binding domain, causing a conformational shift that triggers the activation of the protein and subsequent olfactory signal transduction. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates Olfr426 by fitting into its ligand-binding pocket, which induces a conformational change in the protein structure and activates the olfactory signaling pathway. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol directly interacts with the binding site of Olfr426, inducing a conformational change that activates the protein and the olfactory signaling pathways. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol binds to the active site of Olfr426, leading to a conformational change in the protein and activation of the olfactory signal transduction. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin activates Olfr426 by binding to the receptor's extracellular domain, inducing a structural change necessary for the activation of the olfactory signal transduction cascade. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal activates Olfr426 by interacting with its ligand-binding domain, resulting in a conformational change that triggers the olfactory signaling pathways. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene activates Olfr426 by directly interacting with the ligand-binding domain of the protein, causing a conformational shift that leads to the activation of the olfactory signal transduction mechanisms. | ||||||