Olfr32 Activators
Chemical activators of Olfr32 include a variety of compounds that engage directly with the olfactory receptor, initiating a cascade of cellular events leading to the perception of smell. Citral, for instance, activates Olfr32 by imitating its natural ligand, binding to the receptor and inducing a conformational change that triggers the signal transduction pathway inherent to olfactory neurons. Similarly, eugenol activates Olfr32 through a direct interaction with the receptor's binding site, leading to the activation of G-protein coupled pathways crucial for the function of olfactory neurons. Geraniol and limonene also play their roles in activating Olfr32 by binding to the ligand-binding domain and the receptor site, respectively, which sets off a series of intracellular events translating chemical interactions into olfactory signals.
Furthermore, methyl anthranilate, alpha-pinene, and beta-caryophyllene activate Olfr32 by interacting with different domains of the receptor, triggering a series of cellular responses. Methyl anthranilate does this by interacting with the receptor, leading to odor perception, while alpha-pinene fits into the receptor's active site, activating olfactory signal transduction pathways. Beta-caryophyllene interacts with the transmembrane domain of Olfr32, causing a conformational change and activating downstream signaling molecules. Isoamyl acetate, benzaldehyde, hexanal, phenethyl alcohol, and anisaldehyde all activate Olfr32 by binding to the receptor's ligand-binding region or active site, which induces the necessary changes for signal propagation, perception of odor, and initiation of olfactory-specific pathways. Each of these chemicals initiates a specific molecular interaction with Olfr32, leading to its activation and the subsequent physiological response.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral activates Olfr32 by binding directly to the olfactory receptor, mimicking the natural ligand, and inducing a conformational change that triggers the signal transduction pathway associated with olfactory perception. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol can activate Olfr32 through direct interaction with the receptor's binding site, leading to the activation of G-protein coupled pathways that are integral to the function of olfactory neurons. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol activates Olfr32 by engaging with the protein's ligand-binding domain, initiating a series of intracellular events that translate the chemical interaction into a perceivable olfactory signal. | ||||||
Dipentene | 138-86-3 | sc-252747 | 4 L | $120.00 | ||
Limonene can activate Olfr32 by docking to the olfactory receptor site, causing an activation of the associated G-protein and subsequent signal transduction mechanisms specific to olfaction. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
Alpha-Pinene can activate Olfr32 by directly fitting into the receptor's active site, which leads to the activation of olfactory signal transduction pathways. | ||||||
(−)-trans-Caryophyllene | 87-44-5 | sc-251281 sc-251281A sc-251281B sc-251281C | 1 ml 5 ml 25 ml 1 L | $79.00 $157.00 $437.00 $2861.00 | 1 | |
Beta-Caryophyllene activates Olfr32 by interacting with the protein's transmembrane domain, causing a change in receptor conformation and facilitating the activation of downstream signaling molecules. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isoamyl acetate can activate Olfr32 by binding to the olfactory receptor, mimicking the natural activation process, and inducing the necessary changes for signal propagation. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $26.00 | ||
Hexanal can activate Olfr32 by binding to the receptor's ligand-binding region, which causes a conformational shift that activates the olfactory signaling pathway. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $68.00 | ||
2-Phenylethanol activates Olfr32 by direct engagement with the receptor's active site, leading to activation of the associated G-protein, which is essential for the olfactory signaling process. | ||||||
4-Methoxybenzaldehyde | 123-11-5 | sc-238884 sc-238884A sc-238884B sc-238884C | 5 g 100 g 250 g 1 kg | $29.00 $41.00 $71.00 $122.00 | ||
Anisaldehyde activates Olfr32 by interacting with the receptor, causing a conformational change that leads to signal transduction through olfactory-specific pathways. | ||||||