OIP106 Inhibitors represent a class of chemical compounds that have garnered significant attention in the field of biomedical research and drug discovery due to their potential role in modulating specific cellular processes. These inhibitors are characterized by their ability to selectively target and block the activity of OIP106, a specific protein or enzyme found within biological systems. The acronym "OIP" likely stands for "Overexpressed in Psoriasis," indicating a potential link between OIP106 and dermatological conditions, although it is essential to note that the exact biological functions of OIP106 remain an active area of investigation.
The development and study of OIP106 Inhibitors have primarily revolved around understanding the structural and biochemical properties of OIP106, as well as elucidating its functional significance within cells and tissues. Researchers have employed various techniques, including X-ray crystallography and computational modeling, to gain insights into the three-dimensional structure of OIP106 and to design inhibitors that can specifically bind to and inhibit its activity. These inhibitors may function by disrupting key interactions between OIP106 and its cellular substrates, potentially leading to alterations in signaling pathways or other cellular processes. As a result, OIP106 Inhibitors hold promise as research tools for studying the biology of OIP106.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $153.00 | 5 | |
Ibrutinib is a covalent inhibitor that irreversibly binds to and inhibits the Bruton's tyrosine kinase (BTK), a key enzyme involved in B-cell signaling. This disruption of signaling pathways leads to decreased B-cell proliferation and survival. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Imatinib is a tyrosine kinase inhibitor targeting the BCR-ABL fusion protein in chronic myeloid leukemia (CML). It also inhibits other kinases like KIT and PDGF receptors, reducing cell proliferation and angiogenesis. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
Gefitinib inhibits the epidermal growth factor receptor (EGFR) tyrosine kinase, hindering signal transduction pathways that promote cell growth. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Sorafenib is a multi-kinase inhibitor that targets RAF kinases and the vascular endothelial growth factor receptor (VEGFR), among others. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $206.00 $299.00 $485.00 | 10 | |
Olaparib is a poly(ADP-ribose) polymerase (PARP) inhibitor, interfering with DNA repair mechanisms in cancer cells. It is studied in the research of BRCA-mutated ovarian and breast cancers. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $246.00 $490.00 $536.00 | 16 | |
Ruxolitinib inhibits Janus kinases (JAK1 and JAK2), downregulating cytokine signaling and reducing inflammation. | ||||||
Lapatinib | 231277-92-2 | sc-353658 | 100 mg | $412.00 | 32 | |
Lapatinib is a dual tyrosine kinase inhibitor targeting both EGFR and HER2. It disrupts signaling pathways involved in cell proliferation. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Dasatinib inhibits multiple tyrosine kinases, including BCR-ABL, SRC, and others. |