Date published: 2025-12-8

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OGG Antibodies

Santa Cruz Biotechnology features a diverse variety of OGG Antibodies for the detection and analysis of 8-oxoguanine DNA glycosylase (OGG1), a key enzyme involved in the base excision repair pathway. OGG Antibodies are available for various research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). OGG1 plays a critical role in maintaining genomic stability by recognizing and excising oxidatively damaged guanine bases, which can lead to mutations if left unrepaired. The proper functioning of OGG1 is essential for cellular defense against oxidative stress and is implicated in various diseases, including cancer and neurodegenerative disorders. Understanding the activity and regulation of OGG1 is crucial for advancing therapeutic strategies aimed at enhancing DNA repair mechanisms. Research into OGG1 continues to reveal new insights about its role in maintaining cellular health and preventing disease progression. Investigating OGG1 expression patterns helps scientists better understand DNA repair mechanisms and their impact on disease development. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of DNA repair pathways and their implications in human health.

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OGG Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

OGG1/2 Antibody (G-5)

sc-376935mouse IgG1 κ13-49 (h)WB, IP, IF, ELISAm, r, h
19
(9)

OGG CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OGG1 CRISPR/Cas9 KO Plasmid (m)

sc-422012mGene KnockoutGFP0
(0)

OGG1 HDR Plasmid (m)

sc-422012-HDRmHomology Directed RepairPuromycin0
(0)

OGG1 Double Nickase Plasmid (m)

sc-422012-NICmGene KnockoutPuromycin0
(0)

OGG1 Double Nickase Plasmid (m2)

sc-422012-NIC-2mGene KnockoutPuromycin0
(0)

OGG1/2 CRISPR/Cas9 KO Plasmid (h2)

sc-401130-KO-2hGene KnockoutGFP0
(0)

OGG1/2 HDR Plasmid (h2)

sc-401130-HDR-2hHomology Directed RepairPuromycin0
(0)

OGG1/2 Double Nickase Plasmid (h)

sc-401130-NIChGene KnockoutPuromycin0
(0)

OGG1/2 Double Nickase Plasmid (h2)

sc-401130-NIC-2hGene KnockoutPuromycin0
(0)

OGG CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OGG1 CRISPR Activation Plasmid (m)

sc-422012-ACTmGene ActivationPuro, Blast, Hygro0
(0)

OGG1 CRISPR Activation Plasmid (m2)

sc-422012-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

OGG1 Lentiviral Activation Particles (m)

sc-422012-LACmGene ActivationPuro, Blast, Hygro0
(0)

OGG1 Lentiviral Activation Particles (m2)

sc-422012-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

OGG1/2 CRISPR Activation Plasmid (h)

sc-401130-ACThGene ActivationPuro, Blast, Hygro0
(0)

OGG1/2 CRISPR Activation Plasmid (h2)

sc-401130-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

OGG1/2 Lentiviral Activation Particles (h)

sc-401130-LAChGene ActivationPuro, Blast, Hygro0
(0)

OGG1/2 Lentiviral Activation Particles (h2)

sc-401130-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

OGG siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OGG1 siRNA (m)

sc-44850mGene SilencingN/A
2
(0)

OGG1 shRNA Plasmid (m)

sc-44850-SHmGene SilencingPuromycin
2
(0)

OGG1 shRNA (m) Lentiviral Particles

sc-44850-VmGene SilencingPuromycin
2
(0)

OGG1/2 siRNA (h)

sc-43983hGene SilencingN/A
3
(1)

OGG1/2 shRNA Plasmid (h)

sc-43983-SHhGene SilencingPuromycin
3
(1)

OGG1/2 shRNA (h) Lentiviral Particles

sc-43983-VhGene SilencingPuromycin
3
(1)