NUMB Antibodies

Santa Cruz Biotechnology provides a broad selection of NUMB monoclonal antibodies for research focused on understanding NUMB's role in cellular processes. NUMB monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). NUMB is a critical protein involved in the regulation of cell fate determination and asymmetric cell division, playing a significant role in neural development and the maintenance of stem cell properties. NUMB's function in modulating signaling pathways, such as Notch and Wnt, highlights its importance in both normal physiology and disease states, including cancer. NUMB plays a crucial role in cell differentiation and tissue development during embryogenesis. Research has shown that NUMB acts as a tumor suppressor in various cancers, making it an important target for cancer research. Understanding NUMB's molecular mechanisms can provide valuable insights into developmental biology and potential therapeutic strategies. NUMB monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance their understanding of cellular development and disease mechanisms.