NUDT14 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Methylene blue | 61-73-4 | sc-215381B sc-215381 sc-215381A | 25 g 100 g 500 g | $42.00 $102.00 $322.00 | 3 | |
Methylene Blue can inhibit NUDT14 by interfering with redox reactions and electron transport chains where NUDT14 may play a role, thereby hindering the protein's ability to participate in maintaining cellular redox status. | ||||||
Allopurinol | 315-30-0 | sc-207272 | 25 g | $128.00 | ||
Allopurinol acts as an inhibitor of xanthine oxidase; by reducing the production of uric acid, it can indirectly impede the role of NUDT14 in purine metabolism and thus inhibit its function in the nucleotide salvage pathway. | ||||||
Febuxostat | 144060-53-7 | sc-207680 | 10 mg | $168.00 | 3 | |
Febuxostat selectively inhibits xanthine oxidase, which can indirectly inhibit NUDT14 by altering purine catabolism and the balance of nucleotides in the cell, thereby affecting the purine salvage pathway where NUDT14 is implicated. | ||||||
6-Mercaptopurine | 50-44-2 | sc-361087 sc-361087A | 50 mg 100 mg | $71.00 $102.00 | ||
6-Mercaptopurine gets incorporated into nucleic acids and can inhibit NUDT14 by competing with natural nucleotides, thereby disrupting the nucleotide salvage pathway and the role of NUDT14 in it. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $199.00 $173.00 $342.00 $495.00 $690.00 | 1 | |
Azathioprine is metabolized into 6-mercaptopurine; it can inhibit NUDT14 by interfering with the synthesis and metabolism of natural nucleotides, thus potentially inhibiting the protein's function in the nucleotide salvage pathway. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, leading to decreased DNA synthesis; this can indirectly inhibit NUDT14 by depleting the deoxyribonucleotide pools that NUDT14 may be involved in regulating. | ||||||
Mycophenolate mofetil | 128794-94-5 | sc-200971 sc-200971A | 20 mg 100 mg | $36.00 $107.00 | 1 | |
Mycophenolate Mofetil inhibits inosine monophosphate dehydrogenase, leading to decreased guanine nucleotides; this can inhibit NUDT14 by altering the balance of nucleotides and impeding its role in the guanine salvage pathway. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $62.00 $108.00 $210.00 | 1 | |
Ribavirin, a guanosine analog, can inhibit NUDT14 by mimicking guanosine and thus interfering with the metabolic pathways involving guanine nucleotides where NUDT14 functions. | ||||||
Acyclovir | 59277-89-3 | sc-202906 sc-202906A | 50 mg 500 mg | $147.00 $922.00 | 2 | |
Acyclovir, a guanosine analog, can inhibit NUDT14 by competing with guanine nucleotides, potentially disrupting the protein's function in nucleotide metabolism and salvage pathways. | ||||||
Tiazofurin | 60084-10-8 | sc-475805 | 5 mg | $440.00 | ||
Tiazofurin inhibits inosine monophosphate dehydrogenase, which can lead to an indirect inhibition of NUDT14 by altering the levels of nucleotides, specifically guanine nucleotides, thereby affecting its role in nucleotide salvage pathways. | ||||||