Date published: 2025-12-18

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Nucleic Acids, Nucleotides and Nucleosides

Santa Cruz Biotechnology now offers a broad range of nucleic acids, nucleotides, and nucleosides for use in various applications. Nucleic acids, including DNA and RNA, are the fundamental molecules of life, encoding the genetic information necessary for the development, functioning, and reproduction of all living organisms. Nucleotides, the building blocks of nucleic acids, and nucleosides, which consist of a nitrogenous base attached to a sugar molecule, play critical roles in numerous biological processes. In scientific research, these compounds are essential for studying genetic expression, regulation, and mutation. They are utilized in techniques such as PCR, sequencing, and gene editing, enabling researchers to explore the complexities of genomes and develop innovative biotechnological applications. Nucleic acids are also pivotal in the study of transcription, translation, and replication, providing insights into cellular mechanisms and the flow of genetic information. In the field of molecular biology, nucleotides and nucleosides are used to investigate enzyme activities, signal transduction pathways, and metabolic processes. Environmental scientists study nucleic acids to monitor biodiversity, track microbial communities, and assess environmental changes. Additionally, in materials science, nucleic acids are harnessed for the development of biosensors, nanomaterials, and bioinformatics tools. The broad applicability and vital roles of nucleic acids, nucleotides, and nucleosides in advancing scientific knowledge and technology make them indispensable tools in research across multiple disciplines. View detailed information on our available nucleic acids, nucleotides, and nucleosides by clicking on the product name.

Items 81 to 90 of 156 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Guanosine 5′-Triphosphate, Disodium Salt

56001-37-7sc-295030
sc-295030A
50 mg
250 mg
$163.00
$321.00
(1)

Guanosine 5′-Triphosphate, Disodium Salt is a crucial nucleotide that plays a pivotal role in cellular energy transfer and signaling. Its triphosphate structure allows for high-energy phosphate bonds, facilitating rapid phosphorylation reactions. This compound is integral in the synthesis of RNA and acts as a substrate for various enzymes, influencing metabolic pathways. Its interactions with ribozymes and protein kinases highlight its versatility in regulating biochemical processes.

Uridine 5′-diphosphoglucuronic acid trisodium salt

63700-19-6sc-216043C
sc-216043
sc-216043D
sc-216043A
sc-216043B
5 mg
25 mg
100 mg
250 mg
1 g
$56.00
$106.00
$388.00
$899.00
$2958.00
5
(1)

Uridine 5'-diphosphoglucuronic acid trisodium salt serves as a vital nucleotide in cellular metabolism, particularly in glycosylation reactions. Its unique diphosphate structure enables efficient transfer of glucuronic acid moieties, influencing the conjugation of various substrates. This compound participates in the regulation of carbohydrate metabolism and is involved in the synthesis of glycosaminoglycans. Its interactions with specific enzymes underscore its role in modulating biochemical pathways.

Adenosine 3′,5′-diphosphate disodium salt

75431-54-8sc-210760
sc-210760A
sc-210760B
10 mg
25 mg
100 mg
$325.00
$620.00
$1945.00
2
(1)

Adenosine 3',5'-diphosphate disodium salt is a key nucleotide that plays a crucial role in cellular signaling and energy transfer. Its unique structure allows it to participate in the regulation of cyclic nucleotide pathways, influencing various physiological processes. The compound acts as a substrate for specific kinases, facilitating phosphorylation reactions that modulate enzyme activity. Additionally, its interactions with proteins highlight its importance in signal transduction and metabolic regulation.

3-Deazaneplanocin, HCl salt

120964-45-6sc-351856
sc-351856A
sc-351856B
1 mg
5 mg
10 mg
$251.00
$600.00
$918.00
2
(1)

3-Deazaneplanocin, HCl salt is a potent nucleoside analog that exhibits unique interactions with nucleic acid synthesis pathways. Its structural modifications enable it to inhibit key enzymes involved in RNA and DNA metabolism, thereby altering nucleic acid dynamics. The compound's ability to mimic natural nucleosides allows it to engage in specific binding interactions, influencing reaction kinetics and modulating cellular processes related to nucleic acid turnover and stability.

cADP-Ribose (cADPR)

119340-53-3sc-201512
500 µg
$322.00
2
(1)

cADP-Ribose (cADPR) is a cyclic nucleotide that plays a pivotal role in calcium signaling and cellular processes. It acts as a second messenger, facilitating the release of calcium from intracellular stores. Its unique cyclic structure allows for rapid hydrolysis, influencing reaction kinetics and enabling swift cellular responses. cADPR interacts with various proteins, modulating their activity and impacting pathways such as apoptosis and muscle contraction, showcasing its versatility in cellular signaling.

5-Chloro-2′-deoxyuridine

50-90-8sc-221018
100 mg
$102.00
(3)

5-Chloro-2'-deoxyuridine is a modified nucleoside that incorporates a chlorine atom at the 5-position, influencing its hydrogen bonding and base pairing properties. This alteration can affect the stability of nucleic acid structures and their interactions with polymerases during DNA synthesis. Its unique substitution may also impact the kinetics of incorporation into DNA strands, potentially altering replication fidelity and influencing cellular responses to DNA damage.

Trifluorothymidine

70-00-8sc-222370
sc-222370A
100 mg
1 g
$179.00
$500.00
1
(0)

Trifluorothymidine is a fluorinated nucleoside that features three fluorine atoms, which significantly enhance its hydrophobic character and alter its hydrogen bonding capabilities. This modification can lead to unique interactions with nucleic acid polymerases, potentially affecting the kinetics of nucleotide incorporation. The presence of fluorine may also influence the stability of nucleic acid duplexes, impacting their structural dynamics and reactivity in various biochemical pathways.

N6-Methyladenine

443-72-1sc-236150
250 mg
$178.00
1
(1)

N6-Methyladenine is a modified nucleobase that plays a crucial role in regulating gene expression and cellular processes. Its methyl group can influence base pairing and hydrogen bonding, potentially altering the stability of nucleic acid structures. This modification can affect the recognition by specific enzymes, such as methyltransferases, and may impact the kinetics of DNA replication and repair. Additionally, N6-methylation can modulate chromatin structure, influencing transcriptional activity.

7-Methylxanthine

552-62-5sc-233694
sc-233694A
250 mg
2.5 g
$191.00
$877.00
5
(0)

7-Methylxanthine is a purine derivative that exhibits unique interactions within nucleic acid metabolism. Its structural modifications can influence hydrogen bonding patterns, affecting the stability and conformation of RNA and DNA. This compound participates in various biochemical pathways, potentially altering the kinetics of nucleotide synthesis and degradation. Its presence can also impact the activity of ribonucleases, thereby influencing RNA turnover and cellular signaling processes.

5-Bromo-2′-deoxycytidine

1022-79-3sc-284555
sc-284555A
sc-284555B
sc-284555C
sc-284555D
500 mg
1 g
2 g
5 g
10 g
$204.00
$245.00
$306.00
$561.00
$1020.00
1
(0)

5-Bromo-2'-deoxycytidine is a modified nucleoside that plays a significant role in nucleic acid dynamics. Its bromine substitution enhances base pairing properties, potentially altering the hydrogen bonding landscape in DNA. This compound can influence the replication and repair mechanisms by integrating into DNA strands, affecting polymerase activity and fidelity. Additionally, it may modulate epigenetic modifications, impacting gene expression and chromatin structure.