NP2 Activators
The chemical class NP2 Activators comprises a range of compounds that may indirectly influence the activity of Neuronal Pentraxin 2 (NPTX2) by impacting neuronal activity and synaptic plasticity. NPTX2 is involved in synaptic function and neuronal signaling, and its activity is closely linked to the dynamic processes of synaptic modulation and plasticity.
Compounds such as Tetrodotoxin and Bicuculline affect neuronal excitability by modulating ion channel activity and neurotransmitter receptors. These alterations in neuronal activity could potentially influence the synaptic functions where NPTX2 is involved. Similarly, antagonists of glutamatergic receptors like CNQX (AMPA receptor antagonist) and D-AP5 (NMDA receptor antagonist) may also impact synaptic transmission, potentially leading to changes in NPTX2 activity in response to altered synaptic plasticity. Additionally, compounds that influence intracellular signaling pathways, such as Forskolin and Rolipram, which increase cAMP levels, play a role in this class. The enhancement of synaptic plasticity through elevated cAMP levels could indirectly affect NPTX2's role in synaptic processes. Nitric Oxide Donors and Fluoxetine, by modulating neurotransmitter systems and synaptic transmission, could also indirectly influence NPTX2 activity.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(+)-Bicuculline | 485-49-4 | sc-202498 sc-202498A | 50 mg 250 mg | $82.00 $281.00 | ||
A GABA_A receptor antagonist, could enhance neuronal excitability and potentially influence NPTX2 activity by modulating synaptic plasticity. | ||||||
6-Cyano-7-nitroquinoxaline-2,3-dione | 115066-14-3 | sc-505104 | 10 mg | $208.00 | 2 | |
An AMPA receptor antagonist, potentially affecting glutamatergic synaptic transmission and indirectly influencing NPTX2 activity. | ||||||
D(−)-2-Amino-5-phosphonovaleric acid (D-AP5) | 79055-68-8 | sc-200434 | 5 mg | $97.00 | 2 | |
An NMDA receptor antagonist, potentially influencing synaptic plasticity and indirectly affecting NPTX2 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels. This rise in cAMP can enhance synaptic plasticity, potentially influencing NPTX2 activity. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
A phosphodiesterase inhibitor, increases cAMP levels, potentially enhancing synaptic plasticity and indirectly affecting NPTX2 activity. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
Can modulate neuronal signaling and synaptic plasticity, potentially influencing NPTX2 activity. | ||||||
Fluoxetine | 54910-89-3 | sc-279166 | 500 mg | $318.00 | 9 | |
A selective serotonin reuptake inhibitor, could affect synaptic transmission and potentially influence NPTX2 activity by modulating neuronal activity. | ||||||
(±)-Baclofen | 1134-47-0 | sc-200464 sc-200464A | 1 g 5 g | $56.00 $258.00 | ||
A GABA_B receptor agonist, potentially modulating neuronal activity and influencing NPTX2 activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Used in psychiatric known to affect multiple signaling pathways and might indirectly impact NPTX2 activity through pathways sensitive to lithium's action. | ||||||
Kainic acid | 487-79-6 | sc-200454 sc-200454A sc-200454B sc-200454C sc-200454D | 5 mg 25 mg 100 mg 1 g 5 g | $87.00 $370.00 $1377.00 $7803.00 $24970.00 | 12 | |
A potent agonist for kainate receptors, could modulate excitatory synaptic transmission and indirectly influence NPTX2 activity. | ||||||