Nectin 4 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Erlotinib, Free Base | 183321-74-6 | sc-396113 sc-396113A sc-396113B sc-396113C sc-396113D | 500 mg 1 g 5 g 10 g 100 g | $87.00 $135.00 $293.00 $505.00 $3827.00 | 42 | |
Erlotinib is an EGFR inhibitor that can inhibit Nectin 4 by blocking the EGFR signaling pathway, which is associated with cell adhesion processes that Nectin 4 is involved in, leading to a functional inhibition of Nectin 4's role in this pathway. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
Gefitinib is another EGFR inhibitor that impedes the EGFR pathway, in which Nectin 4 participates. By inhibiting this pathway, Gefitinib functionally inhibits Nectin 4's role in cellular adhesion and signaling. | ||||||
Lapatinib | 231277-92-2 | sc-353658 | 100 mg | $420.00 | 32 | |
Lapatinib inhibits the HER2/neu and EGFR pathways, which are related to cell adhesion processes that involve Nectin 4. Inhibition of these pathways leads to decreased Nectin 4 function in cellular signaling and adhesion mechanisms. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $153.00 $938.00 | 5 | |
Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor that can interfere with pathways linked to Nectin 4 function. Its inhibition of these pathways consequently leads to a functional inhibition of Nectin 4. | ||||||
Afatinib-d4 | 850140-72-6 (unlabeled) | sc-481821 | 10 mg | $4665.00 | ||
Afatinib is an irreversible inhibitor of EGFR, which is part of a pathway that includes Nectin 4. By inhibiting EGFR, Afatinib functionally inhibits Nectin 4 by obstructing its associated signaling processes. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
Sorafenib is a kinase inhibitor that affects various pathways, including those in which Nectin 4 is involved. Its broad inhibition of kinases leads to a decrease in Nectin 4 functional activity within these pathways. | ||||||
Vandetanib | 443913-73-3 | sc-220364 sc-220364A | 5 mg 50 mg | $167.00 $1353.00 | ||
Vandetanib is an inhibitor of VEGFR, EGFR, and RET kinases. Nectin 4, through its association with these pathways, is functionally inhibited by Vandetanibs action on these kinases, leading to reduced Nectin 4 activity. | ||||||
Pazopanib | 444731-52-6 | sc-396318 sc-396318A | 25 mg 50 mg | $130.00 $182.00 | 2 | |
Pazopanib is a multi-kinase inhibitor that can hinder pathways involving Nectin 4. Its inhibition of these kinases decreases the functional activity of Nectin 4 within the affected pathways. | ||||||
Lenvatinib | 417716-92-8 | sc-488530 sc-488530A sc-488530B | 5 mg 25 mg 100 mg | $182.00 $661.00 $1690.00 | 3 | |
Lenvatinib is a multi-targeted tyrosine kinase inhibitor that can functionally inhibit the activity of Nectin 4 by obstructing pathways that Nectin 4 is known to be involved in, particularly in cell signaling and adhesion. | ||||||
XL-184 free base | 849217-68-1 | sc-364657 sc-364657A | 5 mg 10 mg | $94.00 $208.00 | 1 | |
Cabozantinib, by inhibiting MET and VEGFR2, affects pathways that include Nectin 4. The inhibition of these pathways can lead to a functional inhibition of Nectin 4's role within them. | ||||||