NDUFA6 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Rotenone is an inhibitor of mitochondrial complex I and may indirectly downregulate NDUFA6 expression by disrupting the electron transport chain and inducing compensatory mechanisms that alter nuclear-encoded mitochondrial gene expression. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin intercalates DNA and inhibits topoisomerase II, which could lead to decreased transcription of mitochondrial genes, including NDUFA6, as a secondary effect of nuclear genome stress. | ||||||
Actinonin | 13434-13-4 | sc-201289 sc-201289B | 5 mg 10 mg | $170.00 $385.00 | 3 | |
Actinonin is a peptide deformylase inhibitor, which could potentially affect mitochondrial protein synthesis and thus influence NDUFA6 expression indirectly through impaired maturation of mitochondrial proteins. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine can elevate lysosomal pH, which might disrupt protein degradation pathways, possibly leading to misfolded protein response and altered expression of mitochondrial proteins, including NDUFA6. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $56.00 $183.00 $352.00 | 1 | |
Cadmium is known to induce mitochondrial dysfunction and could thereby influence the expression of mitochondrial proteins such as NDUFA6 through cellular stress responses. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide stabilizes the DNA-topoisomerase II complex, preventing DNA relegation and potentially affecting the transcription of genes, including mitochondrial genes like NDUFA6, as part of a cellular stress response. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Antimycin A binds to complex III and inhibits the electron transport chain, which might reduce the expression of other components in the chain, such as NDUFA6, due to disrupted mitochondrial signaling. | ||||||
Tetracycline | 60-54-8 | sc-205858 sc-205858A sc-205858B sc-205858C sc-205858D | 10 g 25 g 100 g 500 g 1 kg | $63.00 $94.00 $270.00 $417.00 $634.00 | 6 | |
Tetracycline is known to affect mitochondrial protein synthesis in eukaryotes as mitochondria have similarities to bacteria, potentially reducing the expression of mitochondrial-encoded proteins like NDUFA6. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
α-Amanitin is a potent inhibitor of RNA polymerase II, which could lead to general inhibition of mRNA synthesis, including that of nuclear-encoded mitochondrial genes like NDUFA6. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Bisphenol A can act as an endocrine disruptor and has been shown to influence gene expression, which might include effects on genes encoding mitochondrial proteins such as NDUFA6. | ||||||